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Viruses 2013, 5(5), 1272-1291; doi:10.3390/v5051272
Review

The Dynamics of HCF-1 Modulation of Herpes Simplex Virus Chromatin during Initiation of Infection

 and *
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bld. 33, 33 North Drive, Bethesda, MD 20892, USA
* Author to whom correspondence should be addressed.
Received: 11 April 2013 / Revised: 14 May 2013 / Accepted: 14 May 2013 / Published: 22 May 2013
(This article belongs to the Special Issue Chromatin Control of Viral Infection)
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Abstract

Successful infection of herpes simplex virus is dependent upon chromatin modulation by the cellular coactivator host cell factor-1 (HCF-1). This review focuses on the multiple chromatin modulation components associated with HCF-1 and the chromatin-related dynamics mediated by this coactivator that lead to the initiation of herpes simplex virus (HSV) immediate early gene expression.
Keywords: herpes simplex virus; chromatin; HCF-1; Setd1A; latency; histone demethylase herpes simplex virus; chromatin; HCF-1; Setd1A; latency; histone demethylase
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Vogel, J.L.; Kristie, T.M. The Dynamics of HCF-1 Modulation of Herpes Simplex Virus Chromatin during Initiation of Infection. Viruses 2013, 5, 1272-1291.

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