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Viruses 2013, 5(5), 1272-1291; doi:10.3390/v5051272

The Dynamics of HCF-1 Modulation of Herpes Simplex Virus Chromatin during Initiation of Infection

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bld. 33, 33 North Drive, Bethesda, MD 20892, USA
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Received: 11 April 2013 / Revised: 14 May 2013 / Accepted: 14 May 2013 / Published: 22 May 2013
(This article belongs to the Special Issue Chromatin Control of Viral Infection)
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Abstract

Successful infection of herpes simplex virus is dependent upon chromatin modulation by the cellular coactivator host cell factor-1 (HCF-1). This review focuses on the multiple chromatin modulation components associated with HCF-1 and the chromatin-related dynamics mediated by this coactivator that lead to the initiation of herpes simplex virus (HSV) immediate early gene expression.
Keywords: herpes simplex virus; chromatin; HCF-1; Setd1A; latency; histone demethylase herpes simplex virus; chromatin; HCF-1; Setd1A; latency; histone demethylase
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Vogel, J.L.; Kristie, T.M. The Dynamics of HCF-1 Modulation of Herpes Simplex Virus Chromatin during Initiation of Infection. Viruses 2013, 5, 1272-1291.

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