Viruses 2011, 3(3), 254-259; doi:10.3390/v3030254
Commentary

A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission

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Received: 15 February 2011; in revised form: 2 March 2011 / Accepted: 2 March 2011 / Published: 9 March 2011
(This article belongs to the Section Editorial)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Retroviruses like HIV-1 and HTLV-1 can be transmitted efficiently by direct contact between infected and target cells. For HIV-1, various modes of cell-to-cell transfer have been reported, including virological synapses, polysynapses, filopodial bridges, and nanotube-like structures. So far, only synapses and biofilms have been described for HTLV-1 transmission. Recently, Van Prooyen et al. [1] identified an additional mode of HTLV-1 transmission through cellular conduits induced by the viral accessory protein p8.
Keywords: HTLV-1; HIV-1; cell-to-cell transfer; virological synapses; cellular conduits; p8; p12; Nef
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MDPI and ACS Style

Malbec, M.; Roesch, F.; Schwartz, O. A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission. Viruses 2011, 3, 254-259.

AMA Style

Malbec M, Roesch F, Schwartz O. A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission. Viruses. 2011; 3(3):254-259.

Chicago/Turabian Style

Malbec, Marine; Roesch, Ferdinand; Schwartz, Olivier. 2011. "A New Role for the HTLV-1 p8 Protein: Increasing Intercellular Conduits and Viral Cell-to-Cell Transmission." Viruses 3, no. 3: 254-259.

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