ࡱ > t bjbj<< 8 ^ ^ q h h < K < " f f f f " " " " " " " $ 1$ & h 4" Q f b f f f 4" " 4 4 4 f d 8 " 4 f " 4 4 \ uIU, . t ! " 0 " | ;' p ;' ;' z f f 4 f f f f f 4" 4" h f f f " f f f f ;' f f f f f f f f f h q : Supplementary Table 1. PLV proviral and FIV mRNA loads (Mean SE) among tissues for single and co-infected cats.
TissueSingleCo-InfectedMeanSEMeanSEPLV proviral copies/106 cellsBone marrow0.000.0010.706.65Thymus0.780.7820.7014.72Spleen230.78149.4594.7565.37Liver7.145.7216.627.51Pre-scapular LN *261.92247.29247.18138.74Mesenteric LN *333.28206.80104.8036.26Peyer's patch97.2252.04230.6086.38Duodenum140.8846.43145.9668.56Jejunum129.32101.5069.40 4 2 . 6 0 I l e u m 2 7 6 . 6 0 1 5 8 . 3 8 1 2 0 . 1 0 5 1 . 0 2 C o l o n i c L N * 5 0 5 . 6 4 4 2 8 . 8 3 2 6 8 . 8 1 1 9 0 . 4 9 T o n s i l 1 0 . 0 2 4 . 9 2 1 1 . 5 1 9 . 6 4 F I V m R N A r e l a t i v e e x p r e s s i o n ( 1 0 "2 ) B o n e m a r r o w 6 1 . 3 4 3 0 . 6 5 1 0 . 2 9 2 . 7 6 T h y m u s 2 6 6 . 2 4 2 3 3 . 6 3 1 1 9 . 4 2 6 2 . 5 0 S p l e e n 1 2 2 . 7 0 9 5 . 6 2 1 7 . 2 8 8 . 8 9 Liver2.311.300.070.02Pre-scapular LN *8.394.743.812.56Mesenteric LN *12.3710.327.053.63Peyer's patch8.917.162.570.43Duodenum6.394.774.062.20Jejunum1.781.402.582.42Ileum16.066.586.853.21Colonic LN *19.4010.874.712.62Tonsil14.4610.281.920.77* LN = lymph node.
Supplementary Table 2. IL-10 and IL-12 mRNA expression (Mean SE) among tissues for FIV single and PLV/FIV co-infected cats.
TissueFIV SinglePLV/FIV co-InfectedMeanSEMeanSEIL-10 mRNA rela t i v e e x p r e s s i o n ( 1 0 "3 ) B o n e m a r r o w 1 . 3 1 0 . 2 0 2 . 4 3 0 . 9 1 T h y m u s 1 1 . 4 3 5 . 8 0 1 7 . 0 9 5 . 4 2 S p l e e n 1 3 . 1 5 4 . 9 9 8 . 2 9 2 . 3 9 L i v e r 4 . 4 9 2 . 4 8 1 . 5 3 0 . 1 8 P r e - s c a p u l a r L N * 7 . 9 4 2 . 8 3 1 6 . 4 2 4 . 2 5 M e s e n t e r i c L N * 3 . 1 3 0 . 9 1 5 . 5 2 0 . 7 1 P e y e r ' s p a t c h 2 4 . 7 2 1 8 . 7 3 9 . 9 8 1 . 0 6 D u o d e n u m 6 . 0 4 4 . 8 1 6 . 6 0 2 . 7 2 J e j u n u m 1 . 0 0 0 . 6 6 5 . 4 4 3 . 9 4 I l e u m 1 8 . 7 5 1 1 . 3 8 6 . 5 5 1 . 4 2 C o l o n i c L N * 6 . 6 3 1 . 0 3 1 0 . 3 8 3 . 0 8 T o n s i l 1 1 . 1 5 3 . 7 4 1 1 . 5 8 2 . 8 7 I L - 1 2 m R N A r e l a t i v e e x p r e s s i o n ( 1 0 "3 ) B o n e m a r r o w 1 . 7 9 0 . 5 0 3 . 3 6 1 . 4 0 T h y m u s 1 8 9 . 0 5 8 6 . 3 9 4 7 . 4 0 ! # r s ! " = > M ϸϧϧ}f}UUUUU hx; haA CJ OJ PJ QJ aJ ,hx; hFB B*CJ H*OJ PJ QJ aJ ph )hx; hFB B*CJ OJ PJ QJ aJ ph )hx; haA B*CJ OJ PJ QJ aJ ph hx; h CJ OJ PJ QJ aJ ,hx; hT 5B*CJ OJ PJ QJ aJ ph ,hx; h 5B*CJ OJ PJ QJ aJ ph h" h" hFB h" h" 5 hFB 5 s z C 5 d $If gdx; kd $$If T l 4 F tb& & &j
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l a yt| T $d $If a$gdx; \ kd $$If T l 0 tb& &
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l a yt| T $d $If a$gdx; d $If gdx; B 4 # $d $If a$gdx; d $If gdx; kd $$If T l r t vb& &B &B &~ &
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l a yt| T 1 kd $$If T l r t vb& &B &B &~ &
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l a yt| T $d $If a$gdx; ! $d $If a$gdx; d $If gdx; ! " ( - B 4 # $d $If a$gdx; d $If gdx; kdr $$If T l r t vb& &B &B &~ &
t 0 6 4 4
l a yt| T - 2 8 = > 1 kdR $$If T l r t vb& &B &B &~ &
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l a yt| T $d $If a$gdx; - 2 7 < A $d $If a$gdx; d $If gdx; A B R X B 4 # $d $If a$gdx; d $If gdx; kd $$If T l r t vb& &B &B &~ &
t 0 6 4 4
l a yt| T X ^ c h i 1 kdh $$If T l r t vb& &B &B &~ &
t 0 6 4 4
l a yt| T $d $If a$gdx; i w | $d $If a$gdx; d $If gdx; B 4 # $d $If a$gdx; d $If gdx; kdH $$If T l r t vb& &B &B &~ &
t 0 6 4 4
l a yt| T 1 kd( $$If T l r t vb& &B &B &~ &
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l a p2 yt| T $d $If a$gdT > 0 d $If gdT kd^ $$If T l r t Dv&&G&&2&8
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l a p2 yt| T $d $If a$gdT " F > 0 d $If gdT kd\ $$If T l r t Dv&&G&&2&8
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l a p2 yt| T $d $If a$gdT F P Z f p r > kdZ $$If T l r t Dv&&G&&2&8
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l a p2 yt| T $d $If a$gdT r $d $If a$gdT d $If gdT O A 0 0 0 $d $If a$gdT d $If gdT kdX $$If T l r t Dv&&G&&2&8
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l a p2 yt| T $d $If a$gdT \ f p z | > 0 d $If gdT kdR# $$If T l r t Dv&&G&&2&8
t 6 4 4
l a p2 yt| T $d $If a$gdT > kdP$ $$If T l r t Dv&&G&&2&8
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t 6 4 4
l a p2 yt| T , 6 8 : > 0 d $If gdT kdL& $$If T l r t Dv& &G & &2 &8
t 6 4 4
l a p2 yt| T $d $If a$gdT x x x x $d $If a$gdT d $If gdT h kdX' $$If T l 0 t& &:
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l a p yt| T O A 0 0 0 $d $If a$gdT d $If gdT kd( $$If T l r t Dv& &G & &2 &8
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l a p2 yt| T 16.98Spleen59.1542.2534.6114.75Liver18.7415.393.530.58Pre-scapular LN *48.4618.47127.1049.32Mesenteric LN *24.334.3723.344.23Peyer's patch15.216.6329.539.10Duodenum65.4855.5717.295.00Jejunum6.652.5016.007.38Ileum63.5725.0311.232.20Colonic LN *77.0130.7450.5613.68Tonsil35.6014.9527.055.15* LN = lymph node.
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l a p2 yt| T $d $If a$gdT & ' - 3 > 0 d $If gdT kd* $$If T l r t Dv&&G&&2&8
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l a p2 yt| T $d $If a$gdT 3 9 > C D V > 0 d $If gdT kd + $$If T l r t Dv&&G&&2&8
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l a p2 yt| T $d $If a$gdT & , 2 8 > $d $If a$gdT d $If gdT > ? F L R X O A 0 0 0 $d $If a$gdT d $If gdT kd1 $$If T l r t Dv& &G & &2 &8
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l a p2 yt| T X ] ^ q r s > 1 / / $d a$gd@, kd2 $$If T l r t Dv& &G & &2 &8
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l a p2 yt| T $d $If a$gdT s t $d a$gd@, 6 &P 1h:p . A!"#$% R2 $$If !v h5 55j #v #v#vj :V l 4
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t 6 , 5 5G552589 / p2 yt| T $$If !v h5 5G55258#v #vG#v#v2#v8:V l
t 6 , 5 5G552589 / p2 yt| T $$If !v h5 5G55258#v #vG#v#v2#v8:V l
t 6 , 5 5G552589 / p2 yt| T $$If !v h5 5G55258#v #vG#v#v2#v8:V l
t 6 , 5 5G552589 / p2 yt| T $$If !v h5 5G55258#v #vG#v#v2#v8:V l
t 6 , 5 5G552589 / p2 yt| T $$If !v h5 5G55258#v #vG#v#v2#v8:V l
t 6 , 5 5G552589 / p2 yt| T
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p yt| T
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t 6 , 5 5G552589 / / p2 yt| T $$If !v h5 5G55258#v #vG#v#v2#v8:V l
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t 6 , 5 5G552589 / p2 yt| T $$If !v h5 5G55258#v #vG#v#v2#v8:V l
t 6 , 5 5G552589 / p2 yt| T $$If !v h5 5G55258#v #vG#v#v2#v8:V l
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t 6 , 5 5G552589 / p2 yt| T $$If !v h5 5G55258#v #vG#v#v2#v8:V l
t 6 , 5 5G552589 / p2 yt| T $$If !v h5 5G55258#v #vG#v#v2#v8:V l
t 6 , 5 5G552589 / p2 yt| T $$If !v h5 5G55258#v #vG#v#v2#v8:V l
t 6 , 5 5G552589 / p2 yt| T $$If !v h5 5G55258#v #vG#v#v2#v8:V l
t 6 , 5 5G552589 / p2 yt| T
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