Next Article in Journal
Retrovirus Integrase-DNA Structure Elucidates Concerted Integration Mechanisms
Previous Article in Journal
The Role of Lipids in Retrovirus Replication
Previous Article in Special Issue
Interactions of Host Proteins with the Murine Leukemia Virus Integrase
Viruses 2010, 2(5), 1181-1184; doi:10.3390/v2051181

Special Issue: Retroviral Enzymes

Received: 5 May 2010 / Accepted: 7 May 2010 / Published: 7 May 2010
(This article belongs to the Special Issue Retroviral Enzymes)
View Full-Text   |   Download PDF [152 KB, uploaded 7 May 2010]
Note: In lieu of an abstract, this is an excerpt from the first page.

Excerpt: The retroviral RNA genome encodes for three enzymes essential for virus replication: (i) the viral protease (PR), that converts the immature virion into a mature virus through the cleavage of precursor polypeptides; (ii) the reverse transcriptase (RT), responsible for the conversion of the single-stranded genomic RNA into double-stranded proviral DNA; and (iii) the integrase (IN) that inserts the proviral DNA into the host cell genome. All of them are important targets for therapeutic intervention. This Special Issue provides authoritative reviews on the most recent research towards a better understanding of structure-function relationships in retroviral enzymes. The Issue includes three reviews on retroviral PRs, seven on RT and reverse transcription, and four dedicated to viral integration. [...]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |

MDPI and ACS Style

Menéndez-Arias, L. Special Issue: Retroviral Enzymes. Viruses 2010, 2, 1181-1184.

AMA Style

Menéndez-Arias L. Special Issue: Retroviral Enzymes. Viruses. 2010; 2(5):1181-1184.

Chicago/Turabian Style

Menéndez-Arias, Luis. 2010. "Special Issue: Retroviral Enzymes." Viruses 2, no. 5: 1181-1184.

Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert