Next Article in Journal
Expert Views on HPV Infection
Previous Article in Journal
Infection and Transport of Herpes Simplex Virus Type 1 in Neurons: Role of the Cytoskeleton
Article Menu
Issue 2 (February) cover image

Export Article

Open AccessReview
Viruses 2018, 10(2), 93; doi:10.3390/v10020093

MERS-CoV: Understanding the Latest Human Coronavirus Threat

Molecular Biology and Virology Research Laboratory, Department of Medical Biosciences, Faculty of Natural Sciences, University of the Western Cape, Private Bag X17, Robert Sobukwe Drive, Bellville 7535, South Africa
Author to whom correspondence should be addressed.
Received: 29 November 2017 / Revised: 28 January 2018 / Accepted: 2 February 2018 / Published: 24 February 2018
(This article belongs to the Section Animal Viruses)
View Full-Text   |   Download PDF [511 KB, uploaded 24 February 2018]   |  


Human coronaviruses cause both upper and lower respiratory tract infections in humans. In 2012, a sixth human coronavirus (hCoV) was isolated from a patient presenting with severe respiratory illness. The 60-year-old man died as a result of renal and respiratory failure after admission to a hospital in Jeddah, Saudi Arabia. The aetiological agent was eventually identified as a coronavirus and designated Middle East respiratory syndrome coronavirus (MERS-CoV). MERS-CoV has now been reported in more than 27 countries across the Middle East, Europe, North Africa and Asia. As of July 2017, 2040 MERS-CoV laboratory confirmed cases, resulting in 712 deaths, were reported globally, with a majority of these cases from the Arabian Peninsula. This review summarises the current understanding of MERS-CoV, with special reference to the (i) genome structure; (ii) clinical features; (iii) diagnosis of infection; and (iv) treatment and vaccine development. View Full-Text
Keywords: human coronavirus; MERS-CoV; clinical features; upper respiratory tract infections; lower respiratory tract infections; respiratory viruses human coronavirus; MERS-CoV; clinical features; upper respiratory tract infections; lower respiratory tract infections; respiratory viruses

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Chafekar, A.; Fielding, B.C. MERS-CoV: Understanding the Latest Human Coronavirus Threat. Viruses 2018, 10, 93.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Viruses EISSN 1999-4915 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top