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Viruses 2018, 10(1), 42; https://doi.org/10.3390/v10010042

Vaccinia Virus in Blood Samples of Humans, Domestic and Wild Mammals in Brazil

1
Faculdade de Medicina Veterinária e Zootecnia, UNESP—Universidade Estadual Paulista, Botucatu CEP 18618-970, Brazil
2
Faculdade de Medicina Veterinária e Zootecnia, USP—Universidade de São Paulo, São Paulo CEP 05508-270, Brazil
3
Instituto de Ciências Biológicas, UFMG—Universidade Federal de Minas Gerais, Belo Horizonte CEP 31270-901, Brazil
*
Author to whom correspondence should be addressed.
Received: 26 November 2017 / Revised: 10 January 2018 / Accepted: 17 January 2018 / Published: 18 January 2018
(This article belongs to the Special Issue Smallpox and Emerging Zoonotic Orthopoxviruses: What Is Coming Next?)
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Abstract

Outbreaks of Vaccinia virus (VACV) affecting cattle and humans have been reported in Brazil in the last 15 years, but the origin of outbreaks remains unknown. Although VACV DNA have been already detected in mice (Mus musculus), opossums (Didelphis albiventris) and dogs during VACV zoonotic outbreaks, no transmission to cattle or humans from any of these were reported during Brazilian outbreaks. In this work, we assessed the PCR positivity to VACV in blood samples of cows and other domestic mammals, wild rodents and other wild mammals, and humans from areas with or without VACV infection reports. Our results show the detection of VACV DNA in blood samples of cows, horse and opossums, raising important questions about VACV spread. View Full-Text
Keywords: Vaccinia virus; blood samples; humans; domestic mammals; wild mammals; public health; epidemiology; transmission Vaccinia virus; blood samples; humans; domestic mammals; wild mammals; public health; epidemiology; transmission
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Peres, M.G.; Bacchiega, T.S.; Appolinário, C.M.; Vicente, A.F.; Mioni, M.S.R.; Ribeiro, B.L.D.; Fonseca, C.R.S.; Pelícia, V.C.; Ferreira, F.; Oliveira, G.P.; Abrahão, J.S.; Megid, J. Vaccinia Virus in Blood Samples of Humans, Domestic and Wild Mammals in Brazil. Viruses 2018, 10, 42.

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