CRISPR-Cas Targeting of Host Genes as an Antiviral Strategy
AbstractCurrently, a new gene editing tool—the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) associated (Cas) system—is becoming a promising approach for genetic manipulation at the genomic level. This simple method, originating from the adaptive immune defense system in prokaryotes, has been developed and applied to antiviral research in humans. Based on the characteristics of virus-host interactions and the basic rules of nucleic acid cleavage or gene activation of the CRISPR-Cas system, it can be used to target both the virus genome and host factors to clear viral reservoirs and prohibit virus infection or replication. Here, we summarize recent progress of the CRISPR-Cas technology in editing host genes as an antiviral strategy. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Chen, S.; Yu, X.; Guo, D. CRISPR-Cas Targeting of Host Genes as an Antiviral Strategy. Viruses 2018, 10, 40.
Chen S, Yu X, Guo D. CRISPR-Cas Targeting of Host Genes as an Antiviral Strategy. Viruses. 2018; 10(1):40.Chicago/Turabian Style
Chen, Shuliang; Yu, Xiao; Guo, Deyin. 2018. "CRISPR-Cas Targeting of Host Genes as an Antiviral Strategy." Viruses 10, no. 1: 40.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.