Next Article in Journal
Experimental Study on Tensile Properties of a Novel Porous Metal Fiber/Powder Sintered Composite Sheet
Next Article in Special Issue
Strontium-Substituted Bioceramics Particles: A New Way to Modulate MCP-1 and Gro-α Production by Human Primary Osteoblastic Cells
Previous Article in Journal
A New Superhard Phase and Physical Properties of ZrB3 from First-Principles Calculations
Previous Article in Special Issue
Identification of Specific Hydroxyapatite {001} Binding Heptapeptide by Phage Display and Its Nucleation Effect
Article Menu
Issue 9 (September) cover image

Export Article

Open AccessArticle
Materials 2016, 9(9), 711; doi:10.3390/ma9090711

Fabrication and Physical Evaluation of Gelatin-Coated Carbonate Apatite Foam

1
Department of Oral Surgery, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramotocho, Tokushima 770-8504, Japan
2
Department of Biomaterials, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan
*
Author to whom correspondence should be addressed.
Academic Editors: Patrice Laquerriere and Franz E. Weber
Received: 18 June 2016 / Revised: 28 July 2016 / Accepted: 16 August 2016 / Published: 23 August 2016
(This article belongs to the Special Issue Calcium Phosphate in Biomedical Applications)
View Full-Text   |   Download PDF [13416 KB, uploaded 23 August 2016]   |  

Abstract

Carbonate apatite (CO3Ap) foam has gained much attention in recent years because of its ability to rapidly replace bone. However, its mechanical strength is extremely low for clinical use. In this study, to understand the potential of gelatin-reinforced CO3Ap foam for bone replacement, CO3Ap foam was reinforced with gelatin and the resulting physical characteristics were evaluated. The mechanical strength increased significantly with the gelatin reinforcement. The compressive strength of gelatin-free CO3Ap foam was 74 kPa whereas that of the gelatin-reinforced CO3Ap foam, fabricated using 30 mass % gelatin solution, was approximately 3 MPa. Heat treatment for crosslinking gelatin had little effect on the mechanical strength of the foam. The gelatin-reinforced foam did not maintain its shape when immersed in a saline solution as this promoted swelling of the gelatin; however, in the same conditions, the heat-treated gelatin-reinforced foam proved to be stable. It is concluded, therefore, that heat treatment is the key to the fabrication of stable gelatin-reinforced CO3Ap foam. View Full-Text
Keywords: Carbonate apatite; foam; interconnected porous structure; gelatin; heat treatment Carbonate apatite; foam; interconnected porous structure; gelatin; heat treatment
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Hara, K.; Fujisawa, K.; Nagai, H.; Takamaru, N.; Ohe, G.; Tsuru, K.; Ishikawa, K.; Miyamoto, Y. Fabrication and Physical Evaluation of Gelatin-Coated Carbonate Apatite Foam. Materials 2016, 9, 711.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Materials EISSN 1996-1944 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top