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Materials 2011, 4(1), 288-299; doi:10.3390/ma4010288
Communication

Laser Fabrication of 3D Gelatin Scaffolds for the Generation of Bioartificial Tissues

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Received: 1 December 2010; in revised form: 6 January 2011 / Accepted: 12 January 2011 / Published: 19 January 2011
(This article belongs to the Special Issue Tissue Engineering Scaffolds)
Download PDF [568 KB, uploaded 19 January 2011]
Abstract: In the present work, the two-photon polymerization (2PP) technique was applied to develop precisely defined biodegradable 3D tissue engineering scaffolds. The scaffolds were fabricated via photopolymerization of gelatin modified with methacrylamide moieties. The results indicate that the gelatin derivative (GelMod) preserves its enzymatic degradation capability after photopolymerization. In addition, the developed scaffolds using 2PP support primary adipose-derived stem cell (ASC) adhesion, proliferation and differentiation into the anticipated lineage.
Keywords: scaffolds; computer-aided design; laser fabrication; two-photon polymerization; gelatin; tissue engineering; biodegradation; stem cells; adipose tissue scaffolds; computer-aided design; laser fabrication; two-photon polymerization; gelatin; tissue engineering; biodegradation; stem cells; adipose tissue
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Ovsianikov, A.; Deiwick, A.; Van Vlierberghe, S.; Pflaum, M.; Wilhelmi, M.; Dubruel, P.; Chichkov, B. Laser Fabrication of 3D Gelatin Scaffolds for the Generation of Bioartificial Tissues. Materials 2011, 4, 288-299.

AMA Style

Ovsianikov A, Deiwick A, Van Vlierberghe S, Pflaum M, Wilhelmi M, Dubruel P, Chichkov B. Laser Fabrication of 3D Gelatin Scaffolds for the Generation of Bioartificial Tissues. Materials. 2011; 4(1):288-299.

Chicago/Turabian Style

Ovsianikov, Aleksandr; Deiwick, Andrea; Van Vlierberghe, Sandra; Pflaum, Michael; Wilhelmi, Mathias; Dubruel, Peter; Chichkov, Boris. 2011. "Laser Fabrication of 3D Gelatin Scaffolds for the Generation of Bioartificial Tissues." Materials 4, no. 1: 288-299.


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