When Blood Is Touched

doi:10.3390/ma2041547

Open AccessThis article is

freely available
re-usable

Materials 2009, 2(4), 1547-1557; doi:10.3390/ma2041547

Review

When Blood Is Touched

Leo Vroman

1600 Texas Street, Apt. 1005, Fort Worth, TX 76102, USA

Received: 7 September 2009 / Accepted: 16 October 2009 / Published: 16 October 2009

(This article belongs to the Special Issue Advances in Biomaterials)

Download PDF Full-Text [2500 KB, uploaded 16 October 2009 10:45 CEST]

Abstract: The development of blood-compatible materials is reviewed. It grew from originally simplistic views of physical requirements such as surface charge and wettability, to endothelial cells seeded onto a biodegradable cast, and tissue engineering. In vitro findings grew from the discovery of one specific protein being adsorbed, to that of sequential protein adsorption with complex implications of platelet and white cell adhesion. The main challenge is still the production of small blood vessels (capillaries).

Keywords: blood; surface; interface; biomaterial

Article Statistics

Click here to load and display the download statistics.

Cite This Article

MDPI and ACS Style

Vroman, L. When Blood Is Touched. Materials 2009, 2, 1547-1557.

AMA Style

Vroman L. When Blood Is Touched. Materials. 2009; 2(4):1547-1557.

Chicago/Turabian Style

Vroman, Leo. 2009. "When Blood Is Touched." Materials 2, no. 4: 1547-1557.

Materials EISSN 1996-1944 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert