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Materials 2009, 2(2), 577-612; doi:10.3390/ma2020577
Review

Micro- and Nanoscale Hydrogel Systems for Drug Delivery and Tissue Engineering

 and
*
Department of Chemistry, Fordham University / 441 East Fordham Road, New York 10458, USA
* Author to whom correspondence should be addressed.
Received: 1 March 2009 / Revised: 11 April 2009 / Accepted: 6 May 2009 / Published: 13 May 2009
(This article belongs to the Special Issue Biocompatibility of Materials)
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Abstract

The pursuit for targeted drug delivery systems has led to the development of highly improved biomaterials with enhanced biocompatibility and biodegradability properties. Micro- and nanoscale components of hydrogels prepared from both natural and artificial components have been gaining significant importance due to their potential uses in cell based therapies, tissue engineering, liquid micro-lenses, cancer therapy, and drug delivery. In this review some of the recent methodologies used in the preparation of a number of synthetic hydrogels such as poly(N-isopropylacrylamide) (pNIPAm), poly(ethylene glycol) (PEG), poly(ethylene oxide) (PEO), polyvinyl alcohol methylacrylate co-polymers (PVA-MA) and polylactic acid (PLA), as well as some of the natural hydrogels and their applications have been discussed in detail.
Keywords: hydrogel; micro; nano; drug delivery; tissue engineering; cancer therapy; diabetes; biosensor hydrogel; micro; nano; drug delivery; tissue engineering; cancer therapy; diabetes; biosensor
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Schwall, C.T.; Banerjee, I.A. Micro- and Nanoscale Hydrogel Systems for Drug Delivery and Tissue Engineering. Materials 2009, 2, 577-612.

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