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Materials 2018, 11(8), 1332; https://doi.org/10.3390/ma11081332

Biocompatible/Biodegradable Electrowetting on Dielectric Microfluidic Chips with Fluorinated CTA/PLGA

ASIC and System State Key Lab, School of Microelectronics, Fudan University, Shanghai 200433, China
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Received: 19 June 2018 / Revised: 26 July 2018 / Accepted: 30 July 2018 / Published: 1 August 2018
(This article belongs to the Special Issue Advances in Hybrid Biomaterials)
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Abstract

One of the major hurdles in the development of biocompatible/biodegradable EWOD (Electrowetting-on-dielectric) devices is the biocompatibility of the dielectric and hydrophobic layers. In this study, we address this problem by using reactive ion etching (RIE) to prepare a super-hydrophobic film combining fluorinated cellulose triacetate (CTA) and poly (lactic-co-glycolic acid) (PLGA). The contact angle (CA) of water droplets on the proposed material is about 160°. X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM) characterizations indicate that a slight increase in the surface roughness and the formation of CFx (C-F or CF2) bonds are responsible for the super-hydrophobic nature of the film. Alternating Current (AC) static electrowetting and droplet transportation experiments evidence that contact angle hysteresis and contact line pinning are greatly reduced by impregnating the CTA/PLGA film with silicon oil. Therefore, this improved film could provide a biocompatible alternative to the typical Teflon® or Cytop® films as a dielectric and hydrophobic layer. View Full-Text
Keywords: fluorinated CTA/PLGA; EWOD; biocompatible; super-hydrophobicity fluorinated CTA/PLGA; EWOD; biocompatible; super-hydrophobicity
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Zhang, K.; Chao, L.; Zhou, J. Biocompatible/Biodegradable Electrowetting on Dielectric Microfluidic Chips with Fluorinated CTA/PLGA. Materials 2018, 11, 1332.

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