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Materials 2017, 10(6), 614; doi:10.3390/ma10060614

Performance of a New Al2O3/Ce–TZP Ceramic Nanocomposite Dental Implant: A Pilot Study in Dogs.

Nanomaterials and Nanotechnology Research Centre (CINN), CSIC-University of Oviedo (UO), Avda. de la Vega 4-6, El Entrego, San-Martín del Rey Aurelio 33940, Spain
Nanoker Research, Pol. Ind. Olloniego, Parcela 22A, Nave 5, Oviedo 33660, Spain
Maxillofacial Surgery Department, Madrid-Montepríncipe Hospital, CEU-San Pablo University, Madrid 28003, Spain
Author to whom correspondence should be addressed.
Academic Editor: José Luis Calvo Guirado
Received: 6 April 2017 / Revised: 10 May 2017 / Accepted: 31 May 2017 / Published: 3 June 2017
(This article belongs to the Special Issue Dental Implant Materials)
View Full-Text   |   Download PDF [4499 KB, uploaded 6 June 2017]   |  


Although titanium remains as the prevalent material in dental implant manufacturing new zirconia-based materials that overcome the major drawbacks of the standard 3Y–yttria partially-stabilized zirconia (Y-TZP) are now emerging. In this study, a new ceramic nanocomposite made of alumina and ceria-stabilized TZP (ZCe-A) has been used to produce dental implants with the mechanic and topographic characteristics of a pilot implant design to evaluate bone and soft tissue integration in a dog model (n = 5). Histological cross-section analysis of the implanted ceramic fixations (n = 15) showed not only perfect biocompatibility, but also a high rate of osseous integration (defined as the percentage of bone to implant contact) and soft tissue attachment. This clinical success, in combination with the superior mechanical properties achieved by this Al2O3/Ce-TZP nanocomposite, may place this material as an improved alternative of traditional 3Y-TZP dental implants. View Full-Text
Keywords: ceramic implant; nanocomposite; Ce-TZP; Al-TZP; zirconia implants; in vivo study ceramic implant; nanocomposite; Ce-TZP; Al-TZP; zirconia implants; in vivo study

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Lopez-Píriz, R.; Fernández, A.; Goyos-Ball, L.; Rivera, S.; Díaz, L.A.; Fernández-Domínguez, M.; Prado, C.; Moya, J.S.; Torrecillas, R. Performance of a New Al2O3/Ce–TZP Ceramic Nanocomposite Dental Implant: A Pilot Study in Dogs.. Materials 2017, 10, 614.

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