The Production of Porous Hydroxyapatite Scaffolds with Graded Porosity by Sequential Freeze-Casting
AbstractPorous hydroxyapatite (HA) scaffolds with porosity-graded structures were fabricated by sequential freeze-casting. The pore structures, compressive strengths, and biocompatibilities of the fabricated porous HA scaffolds were evaluated. The porosities of the inner and outer layers of the graded HA scaffolds were controlled by adjusting the initial HA contents of the casting slurries. The interface between the dense and porous parts was compact and tightly adherent. The porosity and compressive strengths of the scaffold were controlled by the relative thicknesses of the dense/porous parts. In addition, the porous HA scaffolds showed good biocompatibility in terms of preosteoblast cell attachment and proliferation. The results suggest that porous HA scaffolds with load-bearing parts have potential as bone grafts in hard-tissue engineering. View Full-Text
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Lee, H.; Jang, T.-S.; Song, J.; Kim, H.-E.; Jung, H.-D. The Production of Porous Hydroxyapatite Scaffolds with Graded Porosity by Sequential Freeze-Casting. Materials 2017, 10, 367.
Lee H, Jang T-S, Song J, Kim H-E, Jung H-D. The Production of Porous Hydroxyapatite Scaffolds with Graded Porosity by Sequential Freeze-Casting. Materials. 2017; 10(4):367.Chicago/Turabian Style
Lee, Hyun; Jang, Tae-Sik; Song, Juha; Kim, Hyoun-Ee; Jung, Hyun-Do. 2017. "The Production of Porous Hydroxyapatite Scaffolds with Graded Porosity by Sequential Freeze-Casting." Materials 10, no. 4: 367.
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