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Materials 2017, 10(11), 1253; doi:10.3390/ma10111253

Remineralization Property of an Orthodontic Primer Containing a Bioactive Glass with Silver and Zinc

Department of Orthodontics, Dental Research Institute, Pusan National University Dental Hospital, Yangsan 50612, Korea
Department of Oral Anatomy, School of Dentistry, Pusan National University, Yangsan 50612, Korea
Department of Orthodontics, School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, USA
Institute of Translational Dental Sciences, Pusan National University, Busan 46241, Korea
Author to whom correspondence should be addressed.
Received: 6 September 2017 / Revised: 15 October 2017 / Accepted: 28 October 2017 / Published: 31 October 2017
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White spot lesions (WSLs) are irreversible damages in orthodontic treatment due to excessive etching or demineralization by microorganisms. In this study, we conducted a mechanical and cell viability test to examine the antibacterial properties of 0.2% and 1% bioactive glass (BAG) and silver-doped and zinc-doped BAGs in a primer and evaluated their clinical applicability to prevent WSLs. The microhardness statistically significantly increased in the adhesive-containing BAG, while the other samples showed no statistically significant difference compared with the control group. The shear bond strength of all samples increased compared with that of the control group. The cell viability of the control and sample groups was similar within 24 h, but decreased slightly over 48 h. All samples showed antibacterial properties. Regarding remineralization property, the group containing 0.2% of the samples showed remineralization properties compared with the control group, but was not statistically significant; further, the group containing 1% of the samples showed a significant difference compared with the control group. Among them, the orthodontic bonding primer containing 1% silver-doped BAG showed the highest remineralization property. The new orthodontic bonding primer used in this study showed an antimicrobial effect, chemical remineralization effect, and WSL prevention as well as clinically applicable properties, both physically and biologically. View Full-Text
Keywords: remineralization; white spot lesion; bioactive glass; silver-doped BAG; zinc-doped BAG remineralization; white spot lesion; bioactive glass; silver-doped BAG; zinc-doped BAG

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Lee, S.-M.; Kim, I.-R.; Park, B.-S.; Lee, D.J.; Ko, C.-C.; Son, W.-S.; Kim, Y.-I. Remineralization Property of an Orthodontic Primer Containing a Bioactive Glass with Silver and Zinc. Materials 2017, 10, 1253.

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