Int. J. Environ. Res. Public Health 2009, 6(11), 2752-2761; doi:10.3390/ijerph6112752
Review

Is There a Link between Wheezing in Early Childhood and Adverse Birth Outcomes? A Systematic Review

Evridiki Patelarou 1,* email, Maria Chochlidaki 2 email, Victoria Vivilaki 3 email and Hero Brokalaki 4 email
1 University Hospital of Heraklion, Crete, 71414 Greece 2 Independent Researcher, Crete, Heraklion, 71500 Greece 3 Department of Midwifery, Technological Educational Institution, Athens, 12210 Greece 4 Faculty of Nursing, University of Athens, 11527 Greece
* Author to whom correspondence should be addressed.
Received: 24 August 2009 / Accepted: 29 October 2009 / Published: 3 November 2009
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Abstract: We aimed to provide a summary of the existing published knowledge on the association between adverse birth outcomes and the development of wheezing during the first two years of life. We carried out a systematic review of epidemiological studies within the MEDLINE database. Epidemiological studies on human subjects, published in English, were included in the review. A comprehensive literature search yielded 72 studies for further consideration. Following the application of the eligibility criteria we identified nine studies. A positive association and an excess risk of wheezing during the first two years of life were revealed for adverse birth outcomes.
Keywords: adverse birth outcomes; low birth weight; preterm; wheezing; respiratory disorder; asthma

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MDPI and ACS Style

Patelarou, E.; Chochlidaki, M.; Vivilaki, V.; Brokalaki, H. Is There a Link between Wheezing in Early Childhood and Adverse Birth Outcomes? A Systematic Review. Int. J. Environ. Res. Public Health 2009, 6, 2752-2761.

AMA Style

Patelarou E, Chochlidaki M, Vivilaki V, Brokalaki H. Is There a Link between Wheezing in Early Childhood and Adverse Birth Outcomes? A Systematic Review. International Journal of Environmental Research and Public Health. 2009; 6(11):2752-2761.

Chicago/Turabian Style

Patelarou, Evridiki; Chochlidaki, Maria; Vivilaki, Victoria; Brokalaki, Hero. 2009. "Is There a Link between Wheezing in Early Childhood and Adverse Birth Outcomes? A Systematic Review." Int. J. Environ. Res. Public Health 6, no. 11: 2752-2761.

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