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Int. J. Environ. Res. Public Health 2018, 15(1), 81; doi:10.3390/ijerph15010081

Lipoprotein-Cholesterol Fractions in Marginalized Roma versus Majority Population

1
Department of Medical and Clinical Biochemistry, Pavol Jozef Šafárik University in Košice Faculty of Medicine, Trieda SNP 1, 04011 Košice, Slovakia
2
Department of Medical and Clinical Biochemistry, Pavol Jozef Šafárik University in Košice Faculty of Medicine, Trieda SNP 1, 04011 Košice, Slovakia; present address: Medirex a.s., Magnezitárska 2/C, 04011 Košice, Slovakia
3
Department of Burns and Reconstructive Surgery, 1st Private Hospital Kosice-Saca, Lúčna 512/55, 04015 Košice-Šaca, Slovakia
4
Department of Gynaecology and Obstetrics, Louis Pasteur University Hospital, Rastislavova 785/43, 04001 Košice, Slovakia
*
Authors to whom correspondence should be addressed.
Received: 30 November 2017 / Revised: 22 December 2017 / Accepted: 27 December 2017 / Published: 6 January 2018
(This article belongs to the Special Issue Roma Health)
View Full-Text   |   Download PDF [2153 KB, uploaded 6 January 2018]   |  

Abstract

The trend of modern clinical biochemistry is to emphasize the composition and the quality of lipoproteins over their quantity. The serum lipoprotein fractions and subfractions were analyzed by the Lipoprint Lipoprotein Subfractions Testing System, the parameters of lipid profile, as total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C) and triacylglycerides (TAG) were determined by an automated selective biochemical analyzer. Our results showed a significantly lower concentration of cholesterol in the LDL fractions 1 and 2 and in the HDL fractions 8 to 10 in Roma compared to the majority population. The most significant differences between Roma and the majority population when considering body mass index (BMI), waist-to-hip ratio and the index of central obesity were in very low-density lipoproteins (VLDL), intermediate-density lipoproteins, fraction A (IDL-A) and LDL-2. The last two listed were significantly higher in the majority population. VLDL was significantly higher in overweight or obese Roma men and in Roma men with central obesity compared to men from the majority population, as well as in Roma women with normal weight and physiological waist-to-hip ratio compared to the women from majority population. Our study is among the first describing the distribution of lipoprotein subfractions in different ethnic groups. View Full-Text
Keywords: Roma people; lipoprotein; cholesterol; atherogenic lipoproteins Roma people; lipoprotein; cholesterol; atherogenic lipoproteins
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MDPI and ACS Style

Hubková, B.; Bódy, G.; Mašlanková, J.; Birková, A.; Frišman, E.; Kraus, V.; Mareková, M. Lipoprotein-Cholesterol Fractions in Marginalized Roma versus Majority Population. Int. J. Environ. Res. Public Health 2018, 15, 81.

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