Next Article in Journal
Adsorption Behavior and Mechanism for the Uptake of Fluoride Ions by Reed Residues
Next Article in Special Issue
Association between Fetal Adipokines and Child Behavioral Problems at Preschool Age: The Hokkaido Study on Environment and Children’s Health
Previous Article in Journal
Spatial and Seasonal Dynamics of Water Environmental Capacity in Mountainous Rivers of the Southeastern Coast, China
Previous Article in Special Issue
Impact of Smoking Ban on Passive Smoke Exposure in Pregnant Non-Smokers in the Southeastern United States
Article Menu
Issue 1 (January) cover image

Export Article

Open AccessFeature PaperArticle
Int. J. Environ. Res. Public Health 2018, 15(1), 102; https://doi.org/10.3390/ijerph15010102

Preventive Effect of Residential Green Space on Infantile Atopic Dermatitis Associated with Prenatal Air Pollution Exposure

1
Department of Occupational and Environmental Medicine, College of Medicine, Ewha Womans University, Seoul 03760, Korea
2
Department of Occupational and Environmental Medicine, School of Medicine, Inha University, Incheon 22212, Korea
3
Department of Pediatrics, College of Medicine, Korea University, Seoul 02841, Korea
4
Taean Environmental Health Center, Taean 32144, Korea
5
Department of Preventive Medicine, College of Medicine, Seoul National University, Seoul 02841, Korea
6
Department of Occupational and Environmental Medicine, Ulsan University Hospital, College of Medicine, University of Ulsan, Ulsan 44033, Korea
7
Department of Preventive Medicine, College of Medicine, Dankook University, Cheonan 31116, Korea
*
Author to whom correspondence should be addressed.
Received: 3 December 2017 / Revised: 28 December 2017 / Accepted: 3 January 2018 / Published: 9 January 2018
(This article belongs to the Special Issue Maternal and Child Health 2018)
Full-Text   |   PDF [946 KB, uploaded 9 January 2018]   |  

Abstract

Few birth cohort studies have examined the role of traffic-related air pollution (TRAP) in the development of infantile atopic dermatitis (AD), but none have investigated the role of preventive factors such as green spaces. The aim of this study was to investigate whether exposure to nitrogen dioxide (NO2) and particulate matter with an aerodynamic diameter of <10 μm (PM10) during pregnancy is associated with increased risk of development of AD in 6-month-old children and also to examine how this association changes with residential green space. This study used prospective data from 659 participants of the Mothers and Children’s Environmental Health study. Subjects were geocoded to their residential addresses and matched with air pollution data modeled using land-use regression. Information on infantile AD was obtained by using a questionnaire administered to the parents or guardians of the children. The association between infantile AD and exposure to NO2 and PM10 was determined using logistic regression models. We assessed the effects of residential green spaces using stratified analyses and by entering product terms into the logistic regression models. The risk of infantile AD significantly increased with an increase in air pollution exposure during the first trimester of pregnancy. The adjusted odds ratio (OR) and 95% confidence interval (CI) were 1.219 (1.023–1.452) per 10 μg/m3 increase in PM10 and 1.353 (1.027–1.782) per 10 ppb increase in NO2. An increase in the green space within 200 m of residence was associated with a decreased risk of AD (OR = 0.996, 95% CI: 0.993–0.999). The stratified analysis of residential green space revealed stronger associations between infantile AD and PM10 and NO2 exposure during the first trimester in the areas in the lower tertiles of green space. This study indicated that exposure to TRAP during the first trimester of pregnancy is associated with infantile AD. Less residential green space may intensify the association between TRAP exposure and infantile AD. View Full-Text
Keywords: child health; atopic dermatitis; greenness; traffic-related air pollution; particulate matter; birth cohort child health; atopic dermatitis; greenness; traffic-related air pollution; particulate matter; birth cohort
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Lee, J.-Y.; Lamichhane, D.K.; Lee, M.; Ye, S.; Kwon, J.-H.; Park, M.-S.; Kim, H.-C.; Leem, J.-H.; Hong, Y.-C.; Kim, Y.; Ha, M.; Ha, E. Preventive Effect of Residential Green Space on Infantile Atopic Dermatitis Associated with Prenatal Air Pollution Exposure. Int. J. Environ. Res. Public Health 2018, 15, 102.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top