Unusual Onset of Celiac Disease and Addison’s Disease in a 12-Year-Old Boy
AbstractBackground: Celiac disease (CD) is an autoimmune disorder deriving from an aberrant adaptive immune response against gluten-containing grains in genetically predisposed subjects. In a number of patients, CD is associated with one or more other autoimmune diseases. Primary Addison’s disease (AD) and CD may co-exist, although this association is relatively uncommon in children. In addition, it is not precisely defined whether a gluten-free diet influences the course of AD. Case presentation: A case of CD in a 12-year-old boy presenting as acute adrenal insufficiency is described here. A gluten-free diet had a significant therapeutic role in this case, wherein most of the clinical signs and symptoms of AD disappeared in a few days. In addition, the dosage of cortisol acetate, initially administered to treat the AD, was able to be rapidly reduced. Conclusion: This case highlights that CD can be associated with AD in children, and a gluten-free diet seems to positively influence the course of AD. View Full-Text
Share & Cite This Article
Miconi, F.; Savarese, E.; Miconi, G.; Cabiati, G.; Rapaccini, V.; Principi, N.; Esposito, S. Unusual Onset of Celiac Disease and Addison’s Disease in a 12-Year-Old Boy. Int. J. Environ. Res. Public Health 2017, 14, 855.
Miconi F, Savarese E, Miconi G, Cabiati G, Rapaccini V, Principi N, Esposito S. Unusual Onset of Celiac Disease and Addison’s Disease in a 12-Year-Old Boy. International Journal of Environmental Research and Public Health. 2017; 14(8):855.Chicago/Turabian Style
Miconi, Francesco; Savarese, Emanuela; Miconi, Giovanni; Cabiati, Gabriele; Rapaccini, Valentina; Principi, Nicola; Esposito, Susanna. 2017. "Unusual Onset of Celiac Disease and Addison’s Disease in a 12-Year-Old Boy." Int. J. Environ. Res. Public Health 14, no. 8: 855.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.