Ambient Air Pollution and Out-of-Hospital Cardiac Arrest in Beijing, China
AbstractAir pollutants are associated with cardiovascular death; however, there is limited evidence of the effects of different pollutants on out-of-hospital cardiac arrests (OHCAs) in Beijing, China. We aimed to investigate the associations of OHCAs with the air pollutants PM2.5–10 (coarse particulate matter), PM2.5 (particles ≤2.5 μm in aerodynamic diameter), nitrogen dioxide (NO2), sulfur dioxide (SO2), carbon monoxide (CO), and ozone (O3) between 2013 and 2015 using a time-stratified case-crossover study design. We obtained health data from the nationwide emergency medical service database; 4720 OHCA cases of cardiac origin were identified. After adjusting for relative humidity and temperature, the highest odds ratios of OHCA for a 10 μg/m3 increase in PM2.5 were observed at Lag Day 1 (1.07; 95% confidence interval (CI): 1.04–1.10), with strong associations with advanced age (aged ≥70 years) (1.09; 95% CI: 1.05–1.13) and stroke history (1.11; 95% CI: 1.06–1.16). PM2.5–10 and NO2 also showed significant associations with OHCAs, whereas SO2, CO, and O3 had no effects. After simultaneously adjusting for NO2 and SO2 in a multi-pollutant model, PM2.5 remained significant. The effects of PM2.5 in the single-pollutant models for cases with hypertension, respiratory disorders, diabetes mellitus, and heart disease were higher than those for cases without these complications; however, the differences were not statistically significant. The results support that elevated PM2.5 exposure contributes to triggering OHCA, especially in those who are advanced in age and have a history of stroke. View Full-Text
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Xia, R.; Zhou, G.; Zhu, T.; Li, X.; Wang, G. Ambient Air Pollution and Out-of-Hospital Cardiac Arrest in Beijing, China. Int. J. Environ. Res. Public Health 2017, 14, 423.
Xia R, Zhou G, Zhu T, Li X, Wang G. Ambient Air Pollution and Out-of-Hospital Cardiac Arrest in Beijing, China. International Journal of Environmental Research and Public Health. 2017; 14(4):423.Chicago/Turabian Style
Xia, Ruixue; Zhou, Guopeng; Zhu, Tong; Li, Xueying; Wang, Guangfa. 2017. "Ambient Air Pollution and Out-of-Hospital Cardiac Arrest in Beijing, China." Int. J. Environ. Res. Public Health 14, no. 4: 423.