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Int. J. Environ. Res. Public Health 2017, 14(12), 1461; doi:10.3390/ijerph14121461

Investigation of Health Effects According to the Exposure of Low Concentration Arsenic Contaminated Ground Water

1
Department of Preventive Medicin, Dong-A University, Busan 49201, Korea
2
Environmental Health Center, Dong-A University, Busan 49201, Korea
3
Gimhae Clinic Occupational Health Center, Inje University, Gimhae 50969, Korea
4
Haman Community Healthcare center, Haman 50461, Korea
5
Department of Earth and Environmental Science, Andong National University, Andong 36729, Korea
6
Department of Dermatology, Dong-A University, Busan 49201, Korea
7
Department of Environmental Engineering, Andong National University, Andong 36729, Korea
*
Author to whom correspondence should be addressed.
Received: 6 October 2017 / Revised: 22 November 2017 / Accepted: 24 November 2017 / Published: 27 November 2017
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Abstract

Recent epidemiological studies have reported adverse health effects, including skin cancer, due to low concentrations of arsenic via drinking water. We conducted a study to assess whether low arsenic contaminated ground water affected health of the residents who consumed it. For precise biomonitoring results, the inorganic (trivalent arsenite (As III) and pentavalent arsenate (As V)) and organic forms (monomethylarsonate (MMA) and dimethylarsinate (DMA)) of arsenic were separately quantified by combining high-performance liquid chromatography and inductively coupled plasma mass spectroscopy from urine samples. In conclusion, urinary As III, As V, MMA, and hair arsenic concentrations were significantly higher in residents who consumed arsenic contaminated ground water than control participants who consumed tap water. But, most health screening results did not show a statistically significant difference between exposed and control subjects. We presume that the elevated arsenic concentrations may not be sufficient to cause detectable health effects. Consumption of arsenic contaminated ground water could result in elevated urinary organic and inorganic arsenic concentrations. We recommend immediate discontinuation of ground water supply in this area for the safety of the residents. View Full-Text
Keywords: arsenic; biomonitoring; health effects arsenic; biomonitoring; health effects
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MDPI and ACS Style

Hong, Y.-S.; Ye, B.-J.; Kim, Y.-M.; Kim, B.-G.; Kang, G.-H.; Kim, J.-J.; Song, K.-H.; Kim, Y.-H.; Seo, J.-W. Investigation of Health Effects According to the Exposure of Low Concentration Arsenic Contaminated Ground Water. Int. J. Environ. Res. Public Health 2017, 14, 1461.

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