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Int. J. Environ. Res. Public Health 2016, 13(8), 801; doi:10.3390/ijerph13080801

Comparison of the Combined Obesity Indices to Predict Cardiovascular Diseases Risk Factors and Metabolic Syndrome in Northeast China

Epidemiology and Biostatistics School of Public Health, NO. 1163 Xinmin Street, Jilin University, Changchun 130021, China
Department of Immunization Program, Changchun Center for Disease Control and Prevention, Changchun 130021, China
Author to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Received: 14 June 2016 / Revised: 28 July 2016 / Accepted: 2 August 2016 / Published: 9 August 2016
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Background: Obesity is associated with cardiovascular disease (CVD) risk factors (hypertension, dyslipidemia and diabetes) and metabolic syndrome (MetS), and it may be flawed that most studies only use one obesity index to predict these risk factors. Therefore, our study aims to compare the various combined obesity indices systematically, and to find the optimal combined obesity indices to predict CVD risk factors and MetS. Methods: A total of 16,766 participants aged 18–79 years old were recruited in Jilin Province in 2012. Receiver operating characteristic curve (ROC) curves and multiple logistic regressions were used to evaluate the predictive capacity of the combined obesity indices for CVD risk factors and MetS. Results: The adjusted area under receiver operating characteristic (AUROC) with two combined obesity indices had been improved up to 19.45%, compared with one single obesity index. In addition, body mass index (BMI) and waist circumference (WC) were the optimal combinations, where the AUROC (95% confidence interval (CI)) for hypertension, dyslipidemia, diabetes and MetS in males were 0.730 (0.718, 0.740), 0.694 (0.682, 0.706), 0.725 (0.709, 0.742) and 0.820 (0.810, 0.830), and in females were 0.790 (0.780, 0.799), 0.727 (0.717, 0.738), 0.746 (0.731, 0.761) and 0.828 (0.820, 0.837), respectively. Conclusions: The more abnormal obesity indices that one has the higher the risk for CVD risk factors and MetS, especially in males. In addition, the combined obesity indices have better predictions than one obesity index, where BMI and WC are the optimal combinations. View Full-Text
Keywords: obesity; cardiovascular diseases; metabolic syndrome; AUROC obesity; cardiovascular diseases; metabolic syndrome; AUROC

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Tao, Y.; Yu, J.; Tao, Y.; Pang, H.; Yu, Y.; Yu, Y.; Jin, L. Comparison of the Combined Obesity Indices to Predict Cardiovascular Diseases Risk Factors and Metabolic Syndrome in Northeast China. Int. J. Environ. Res. Public Health 2016, 13, 801.

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