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Int. J. Environ. Res. Public Health 2016, 13(6), 564; doi:10.3390/ijerph13060564

Nutrient Intakes in Early Life and Risk of Obesity

Université Paris 13, Equipe de Recherche en Epidémiologie Nutritionnelle, Centre de Recherche en Epidémiologie et Statistiques, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cité, Bobigny F-93017, France
Author to whom correspondence should be addressed.
Academic Editor: María M. Morales Suárez-Varela
Received: 11 March 2016 / Revised: 20 May 2016 / Accepted: 26 May 2016 / Published: 6 June 2016
(This article belongs to the Collection Prevent Obesity in the First 1000 Days)
View Full-Text   |   Download PDF [2103 KB, uploaded 6 June 2016]   |  


There is increasing evidence that environmental factors in early life predict later health. The early adiposity rebound recorded in most obese subjects suggests that factors promoting body fat development have operated in the first years of life. Birth weight, growth velocity and body mass index (BMI) trajectories seem to be highly sensitive to the environmental conditions present during pregnancy and in early life (“The first 1000 days”). Particularly, nutritional exposure can have a long-term effect on health in adulthood. The high protein-low fat diet often recorded in young children may have contributed to the rapid rise of childhood obesity prevalence during the last decades. Metabolic programming by early nutrition could explain the development of later obesity and adult diseases. View Full-Text
Keywords: early nutrition; child’s growth; obesity; leptin; metabolic programming; adiposity rebound; epidemiology; secular trends early nutrition; child’s growth; obesity; leptin; metabolic programming; adiposity rebound; epidemiology; secular trends

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Rolland-Cachera, M.F.; Akrout, M.; Péneau, S. Nutrient Intakes in Early Life and Risk of Obesity. Int. J. Environ. Res. Public Health 2016, 13, 564.

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