Next Article in Journal
Exposure to Indoor Pollutants and Wheeze and Asthma Development during Early Childhood
Previous Article in Journal
Exposure to Seasonal Temperatures during the Last Month of Gestation and the Risk of Preterm Birth in Stockholm
Article Menu

Export Article

Open AccessArticle
Int. J. Environ. Res. Public Health 2015, 12(4), 3979-3992; doi:10.3390/ijerph120403979

Let It “B”? The Role of Hepatitis B Universal Vaccination among Italian Problematic Drug Users

1
Department of Internal Medicine, Addiction Unit, Verona University Hospital, Verona 37134, Italy
2
Department of mental health and addictions, Epidemiological Observatory on Pathological Addictions, Bologna 40121, Italy
3
Department of mental health and addictions, Addiction Clinic, Bologna 40121, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Received: 6 January 2015 / Revised: 31 March 2015 / Accepted: 1 April 2015 / Published: 13 April 2015
View Full-Text   |   Download PDF [702 KB, uploaded 13 April 2015]

Abstract

Hepatitis B virus (HBV) hepatitis is extremely common among problematic drug users (DUs). As of 2012, 47 of the 53 European countries had implemented a universal hepatitis B vaccination programme, a scenario that could radically change its spread. Even so, drug users are still one of the main groups at risk of being infected by HBV, exposing the fact that universal vaccination still has not managed to reach an optimal level of contagion protection. In order to evaluate the role of universal HBV vaccination in protecting against risk behaviour related to the use of illicit drugs, a group of 748 DUs, 511 male and 237 female, was tested for HBV markers, at their first access to public addiction clinics in the metropolitan area of Bologna, Italy. 487 were born after 1981, so they were eligible to have received HBV vaccination in adolescence or at birth; in these subjects antibodies against HBV core antigen had the significant prevalence of 6.2%. Universal HBV vaccination has shown evidence of protecting against infection in the general population. These results, amongst the first to evaluate actual protection in DUs vaccinated at birth or during adolescence, show that compulsory universal vaccination does not solve the problem of HBV transmission in the most at risk groups and that additional strategies must be studied and implemented to address this issue. View Full-Text
Keywords: HBV; hepatitis; vaccine; universal vaccination; substance abuse; drug use; addiction HBV; hepatitis; vaccine; universal vaccination; substance abuse; drug use; addiction
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Lugoboni, F.; Pavarin, R.M.; Resentera, C.; Gambini, D. Let It “B”? The Role of Hepatitis B Universal Vaccination among Italian Problematic Drug Users. Int. J. Environ. Res. Public Health 2015, 12, 3979-3992.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Environ. Res. Public Health EISSN 1660-4601 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top