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Int. J. Environ. Res. Public Health 2014, 11(5), 4870-4885; doi:10.3390/ijerph110504870
Article

Hematological and Biochemical Data Obtained in Rural Northern Uganda

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Received: 26 February 2014; in revised form: 21 April 2014 / Accepted: 30 April 2014 / Published: 6 May 2014
View Full-Text   |   Download PDF [202 KB, uploaded 19 June 2014]
Abstract: Reference intervals for common hematological and clinical chemistry parameters constitute an important basis for health care. Moreover, with increasing priority in drug and vaccine development for infectious diseases in Africa, the first priority is the safety evaluation and tolerability of the candidate interventions in healthy populations. To accurately assess health status and address adverse events, clinical reference intervals in the target population are necessary. We report on hematological and biochemical indices from healthy volunteers who participated in a clinical trial in Lira, northern Uganda. Median and nonparametric 95% percentiles on five hematology and 15 biochemistry analytes are shown. Although most hematological analytes conformed to reported reference intervals and trends in Africa, literature review from different African countries highlight the need for a region-specific children reference interval that can be appropriate for the population.
Keywords: reference intervals; clinical trials; hematology; biochemistry; adult reference values; children reference values reference intervals; clinical trials; hematology; biochemistry; adult reference values; children reference values
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Palacpac, N.M.Q.; Ntege, E.; Balikagala, B.; Yeka, A.; Shirai, H.; Suzuki, N.; Nsereko, C.; Kanoi, B.N.; Okada, T.; Egwang, T.G.; Horii, T. Hematological and Biochemical Data Obtained in Rural Northern Uganda. Int. J. Environ. Res. Public Health 2014, 11, 4870-4885.

AMA Style

Palacpac NMQ, Ntege E, Balikagala B, Yeka A, Shirai H, Suzuki N, Nsereko C, Kanoi BN, Okada T, Egwang TG, Horii T. Hematological and Biochemical Data Obtained in Rural Northern Uganda. International Journal of Environmental Research and Public Health. 2014; 11(5):4870-4885.

Chicago/Turabian Style

Palacpac, Nirianne M.Q.; Ntege, Edward; Balikagala, Betty; Yeka, Adoke; Shirai, Hiroki; Suzuki, Nahoko; Nsereko, Christopher; Kanoi, Bernard N.; Okada, Takuya; Egwang, Thomas G.; Horii, Toshihiro. 2014. "Hematological and Biochemical Data Obtained in Rural Northern Uganda." Int. J. Environ. Res. Public Health 11, no. 5: 4870-4885.


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