Int. J. Environ. Res. Public Health 2014, 11(2), 1369-1383; doi:10.3390/ijerph110201369
Article

Detection of Potential Drug-Drug Interactions for Outpatients across Hospitals

1,2email, 3email, 4email, 3email and 3,* email
Received: 17 December 2013; in revised form: 13 January 2014 / Accepted: 14 January 2014 / Published: 27 January 2014
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The National Health Insurance Administration (NHIA) has adopted smart cards (or NHI-IC cards) as health cards to carry patients’ medication histories across hospitals in Taiwan. The aims of this study are to enhance a computerized physician order entry system to support drug-drug interaction (DDI) checking based on a patient’s medication history stored in his/her NHI-IC card. For performance evaluation, we developed a transaction tracking log to keep track of every operation on NHI-IC cards. Based on analysis of the transaction tracking log from 1 August to 31 October 2007, physicians read patients’ NHI-IC cards in 71.01% (8,246) of patient visits; 33.02% (2,723) of the card reads showed at least one medicine currently being taken by the patient, 82.94% of which were prescribed during the last visit. Among 10,036 issued prescriptions, seven prescriptions (0.09%) contained at least one drug item that might interact with the currently-taken medicines stored in NHI-IC cards and triggered pop-up alerts. This study showed that the capacity of an NHI-IC card is adequate to support DDI checking across hospitals. Thus, the enhanced computerized physician order entry (CPOE) system can support better DDI checking when physicians are making prescriptions and provide safer medication care, particularly for patients who receive medication care from different hospitals.
Keywords: drug-drug interactions; health smart cards; CPOE system; system interoperability; patient safety
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MDPI and ACS Style

Yeh, Y.-T.; Hsu, M.-H.; Chen, C.-Y.; Lo, Y.-S.; Liu, C.-T. Detection of Potential Drug-Drug Interactions for Outpatients across Hospitals. Int. J. Environ. Res. Public Health 2014, 11, 1369-1383.

AMA Style

Yeh Y-T, Hsu M-H, Chen C-Y, Lo Y-S, Liu C-T. Detection of Potential Drug-Drug Interactions for Outpatients across Hospitals. International Journal of Environmental Research and Public Health. 2014; 11(2):1369-1383.

Chicago/Turabian Style

Yeh, Yu-Ting; Hsu, Min-Hui; Chen, Chien-Yuan; Lo, Yu-Sheng; Liu, Chien-Tsai. 2014. "Detection of Potential Drug-Drug Interactions for Outpatients across Hospitals." Int. J. Environ. Res. Public Health 11, no. 2: 1369-1383.

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