Mar. Drugs 2011, 9(5), 712-718; doi:10.3390/md9050712
Article

Effects of Oral Glucosamine Hydrochloride Administration on Plasma Free Amino Acid Concentrations in Dogs

1 Department of Veterinary Clinical Medicine, School of Veterinary Medicine, Tottori University, 4-101 Koyama-minami, Tottori 680-8553, Japan 2 Koyo Chemical Co. Ltd., 2-11-1 Koraku, Bunkyoku, Tokyo 112-0004, Japan
* Author to whom correspondence should be addressed.
Received: 23 March 2011; in revised form: 18 April 2011 / Accepted: 25 April 2011 / Published: 27 April 2011
(This article belongs to the Special Issue Marine Functional Food)
PDF Full-text Download PDF Full-Text [191 KB, uploaded 27 April 2011 12:03 CEST]
Abstract: We examined the effects of oral glucosamine hydrochloride (GlcN), N-acetyl-D-glucosamine (GlcNAc) and D-glucose (Glc) administration on plasma total free amino acid (PFAA) concentrations in dogs. The PFAA concentrations increased in the control group and the GlcNAc group at one hour after feeding, and each amino acid concentration increased. On the other hand, in the GlcN group and the Glc group PFAA concentrations decreased at one hour after feeding. A significant decrease in amino acid concentration was observed for glutamate, glycine and alanine. Our results suggest the existence of differences in PFAA dynamics after oral administration of GlcN and GlcNAc in dogs.
Keywords: glucosamine hydrochloride; N-acetyl-D-glucosamine; amino acid; dog

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Azuma, K.; Osaki, T.; Tsuka, T.; Imagawa, T.; Okamoto, Y.; Takamori, Y.; Minami, S. Effects of Oral Glucosamine Hydrochloride Administration on Plasma Free Amino Acid Concentrations in Dogs. Mar. Drugs 2011, 9, 712-718.

AMA Style

Azuma K, Osaki T, Tsuka T, Imagawa T, Okamoto Y, Takamori Y, Minami S. Effects of Oral Glucosamine Hydrochloride Administration on Plasma Free Amino Acid Concentrations in Dogs. Marine Drugs. 2011; 9(5):712-718.

Chicago/Turabian Style

Azuma, Kazuo; Osaki, Tomohiro; Tsuka, Takeshi; Imagawa, Tomohiro; Okamoto, Yoshiharu; Takamori, Yoshimori; Minami, Saburo. 2011. "Effects of Oral Glucosamine Hydrochloride Administration on Plasma Free Amino Acid Concentrations in Dogs." Mar. Drugs 9, no. 5: 712-718.

Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert