Next Article in Journal
Novel Anti-Infective Compounds from Marine Bacteria
Next Article in Special Issue
Generating a Generation of Proteasome Inhibitors: From Microbial Fermentation to Total Synthesis of Salinosporamide A (Marizomib) and Other Salinosporamides
Previous Article in Journal
Primary Screening of the Bioactivity of Brackishwater Cyanobacteria: Toxicity of Crude Extracts to Artemia salina Larvae and Paracentrotus lividus Embryos
Previous Article in Special Issue
Calyculins and Related Marine Natural Products as Serine- Threonine Protein Phosphatase PP1 and PP2A Inhibitors and Total Syntheses of Calyculin A, B, and C
Article Menu

Export Article

Open AccessReview
Mar. Drugs 2010, 8(3), 483-497; doi:10.3390/md8030483

Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa

Alfred-Wegener-Institut für Polar- und Meeresforschung in der Helmholtz-Gemeinschaft, Am Handelshafen 12, D-27570 Bremerhaven, Germany
*
Author to whom correspondence should be addressed.
Received: 21 January 2010 / Revised: 2 March 2010 / Accepted: 2 March 2010 / Published: 5 March 2010
(This article belongs to the Special Issue Synthesis around Marine Natural Products)
View Full-Text   |   Download PDF [390 KB, uploaded 24 February 2015]   |  

Abstract

3-Alkyl pyridinium alkaloids (3-APAs) are common secondary metabolites in marine sponges of the order Haplosclerida. In recent years, our laboratory has isolated and synthesized several new members of this family such as haliclamines C–F, viscosamine, viscosaline and a cyclic monomer. All of them were isolated from the Arctic sponge Haliclona viscosa collected in Spitsbergen, Norway. In this article we report the syntheses of these secondary metabolites from Haliclona viscosa and related compounds and give a short overview of the bioactivity. View Full-Text
Keywords: 3-alkyl pyridinium alkaloids; Haliclona viscosa; synthesis; marine natural products 3-alkyl pyridinium alkaloids; Haliclona viscosa; synthesis; marine natural products
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Timm, C.; Mordhorst, T.; Köck, M. Synthesis of 3-Alkyl Pyridinium Alkaloids from the Arctic Sponge Haliclona viscosa. Mar. Drugs 2010, 8, 483-497.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top