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Mar. Drugs 2010, 8(1), 190-199; doi:10.3390/md8010190

ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis

1
Australian Institute of Marine Science, Townsville, Queensland, 4810, Australia
2
AIMS@JCU, Sir George Fisher Building, James Cook University, Townsville, 4811, Queensland, Australia
3
School of Marine and Tropical Biology, James Cook University, Townsville, 4811, Queensland, Australia
*
Author to whom correspondence should be addressed.
Received: 10 December 2009 / Revised: 19 January 2010 / Accepted: 21 January 2010 / Published: 22 January 2010
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Abstract

The viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884) contains a range of secondary metabolites, including manoalide (1) and manoalide monoacetate (3). ESI (+) FTICR-MS accurate mass determination has, for the first time, been used to detected the presence of 3 only in an organic extract of a single L. variabilis larva showing that the parentally produced 3 is sequestered in the larva. As 3 has previously been shown to have antibacterial and quorum sensing inhibition activity, and readily converts to 1, which also exhibits similar activity, it may provide a chemical defence against predation and microbial attack. View Full-Text
Keywords: Luffariella variabilis; manoalide monoacetate; larvae; ESI FTICR-MS; constitutive defence Luffariella variabilis; manoalide monoacetate; larvae; ESI FTICR-MS; constitutive defence
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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Motti, C.A.; Ettinger-Epstein, P.; Willis, R.H.; Tapiolas, D.M. ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis. Mar. Drugs 2010, 8, 190-199.

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