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ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis
Australian Institute of Marine Science, Townsville, Queensland, 4810, Australia
AIMS@JCU, Sir George Fisher Building, James Cook University, Townsville, 4811, Queensland, Australia
School of Marine and Tropical Biology, James Cook University, Townsville, 4811, Queensland, Australia
* Author to whom correspondence should be addressed.
Received: 10 December 2009; in revised form: 19 January 2010 / Accepted: 21 January 2010 / Published: 22 January 2010
Abstract: The viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884) contains a range of secondary metabolites, including manoalide (1) and manoalide monoacetate (3). ESI (+) FTICR-MS accurate mass determination has, for the first time, been used to detected the presence of 3 only in an organic extract of a single L. variabilis larva showing that the parentally produced 3 is sequestered in the larva. As 3 has previously been shown to have antibacterial and quorum sensing inhibition activity, and readily converts to 1, which also exhibits similar activity, it may provide a chemical defence against predation and microbial attack.
Keywords: Luffariella variabilis; manoalide monoacetate; larvae; ESI FTICR-MS; constitutive defence
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MDPI and ACS Style
Motti, C.A.; Ettinger-Epstein, P.; Willis, R.H.; Tapiolas, D.M. ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis. Mar. Drugs 2010, 8, 190-199.
Motti CA, Ettinger-Epstein P, Willis RH, Tapiolas DM. ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis. Marine Drugs. 2010; 8(1):190-199.
Motti, Cherie A.; Ettinger-Epstein, Piers; Willis, Richard H.; Tapiolas, Dianne M. 2010. "ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis." Mar. Drugs 8, no. 1: 190-199.