Mar. Drugs 2010, 8(1), 190-199; doi:10.3390/md8010190
Article

ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis

1,* email, 2,3email, 1email and 1email
Received: 10 December 2009; in revised form: 19 January 2010 / Accepted: 21 January 2010 / Published: 22 January 2010
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The viviparous Great Barrier Reef sponge Luffariella variabilis (Poléjaeff 1884) contains a range of secondary metabolites, including manoalide (1) and manoalide monoacetate (3). ESI (+) FTICR-MS accurate mass determination has, for the first time, been used to detected the presence of 3 only in an organic extract of a single L. variabilis larva showing that the parentally produced 3 is sequestered in the larva. As 3 has previously been shown to have antibacterial and quorum sensing inhibition activity, and readily converts to 1, which also exhibits similar activity, it may provide a chemical defence against predation and microbial attack.
Keywords: Luffariella variabilis; manoalide monoacetate; larvae; ESI FTICR-MS; constitutive defence
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MDPI and ACS Style

Motti, C.A.; Ettinger-Epstein, P.; Willis, R.H.; Tapiolas, D.M. ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis. Mar. Drugs 2010, 8, 190-199.

AMA Style

Motti CA, Ettinger-Epstein P, Willis RH, Tapiolas DM. ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis. Marine Drugs. 2010; 8(1):190-199.

Chicago/Turabian Style

Motti, Cherie A.; Ettinger-Epstein, Piers; Willis, Richard H.; Tapiolas, Dianne M. 2010. "ESI FTICR-MS Analysis of Larvae from the Marine Sponge Luffariella variabilis." Mar. Drugs 8, no. 1: 190-199.

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