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Marine Toxins Targeting Ion Channels
Mar. Drugs 2006, 4(3), 70-81; doi:10.3390/md403070
Review

Cnidarian Toxins Acting on Voltage-Gated Ion Channels

 and *
Marine Biological Laboratory, 7 MBL Street, Woods Hole, MA 02543, USA
* Author to whom correspondence should be addressed.
Received: 21 February 2006 / Accepted: 27 February 2006 / Published: 6 April 2006
(This article belongs to the Special Issue Marine Drugs and Ion Channels)
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Abstract

Voltage-gated ion channels generate electrical activity in excitable cells. As such, they are essential components of neuromuscular and neuronal systems, and are targeted by toxins from a wide variety of phyla, including the cnidarians. Here, we review cnidarian toxins known to target voltage-gated ion channels, the specific channel types targeted, and, where known, the sites of action of cnidarian toxins on different channels.
Keywords: Cnidaria; ion channels; toxin; sodium channel; potassium channel Cnidaria; ion channels; toxin; sodium channel; potassium channel
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Messerli, S.M.; Greenberg, R.M. Cnidarian Toxins Acting on Voltage-Gated Ion Channels. Mar. Drugs 2006, 4, 70-81.

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