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Cnidarian Toxins Acting on Voltage-Gated Ion Channels
Marine Biological Laboratory, 7 MBL Street, Woods Hole, MA 02543, USA
* Author to whom correspondence should be addressed.
Received: 21 February 2006; Accepted: 27 February 2006 / Published: 6 April 2006
Abstract: Voltage-gated ion channels generate electrical activity in excitable cells. As such, they are essential components of neuromuscular and neuronal systems, and are targeted by toxins from a wide variety of phyla, including the cnidarians. Here, we review cnidarian toxins known to target voltage-gated ion channels, the specific channel types targeted, and, where known, the sites of action of cnidarian toxins on different channels.
Keywords: Cnidaria; ion channels; toxin; sodium channel; potassium channel
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Messerli, S.M.; Greenberg, R.M. Cnidarian Toxins Acting on Voltage-Gated Ion Channels. Mar. Drugs 2006, 4, 70-81.
Messerli SM, Greenberg RM. Cnidarian Toxins Acting on Voltage-Gated Ion Channels. Marine Drugs. 2006; 4(3):70-81.
Messerli, Shanta M.; Greenberg, Robert M. 2006. "Cnidarian Toxins Acting on Voltage-Gated Ion Channels." Mar. Drugs 4, no. 3: 70-81.