Mar. Drugs 2005, 3(2), 29-35; doi:10.3390/md302029
Article

Secomycalolide A: A New Proteasome Inhibitor Isolated from a Marine Sponge of the Genus Mycale

Graduate School of Natural Science and Technology, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan
* Author to whom correspondence should be addressed.
Received: 28 April 2005; Accepted: 25 May 2005 / Published: 1 June 2005
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Abstract: A new oxazole-containing proteasome inhibitor, secomycalolide A, together with known mycalolide A and 30-hydroxymycalolide A, was isolated from a marine sponge of the genus Mycale. They showed proteasome inhibitory activities with IC50 values of 11-45 μg/mL.
Keywords: proteasome inhibitor; secomycalolide A; mycalolide A; marine sponge; Mycale

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MDPI and ACS Style

Tsukamoto, S.; Koimaru, K.; Ohta, T. Secomycalolide A: A New Proteasome Inhibitor Isolated from a Marine Sponge of the Genus Mycale. Mar. Drugs 2005, 3, 29-35.

AMA Style

Tsukamoto S, Koimaru K, Ohta T. Secomycalolide A: A New Proteasome Inhibitor Isolated from a Marine Sponge of the Genus Mycale. Marine Drugs. 2005; 3(2):29-35.

Chicago/Turabian Style

Tsukamoto, Sachiko; Koimaru, Keiichirou; Ohta, Tomihisa. 2005. "Secomycalolide A: A New Proteasome Inhibitor Isolated from a Marine Sponge of the Genus Mycale." Mar. Drugs 3, no. 2: 29-35.

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