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Mar. Drugs 2017, 15(10), 324; https://doi.org/10.3390/md15100324

Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids

1,2
,
1,* and 1,*
1
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu Chong Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China
2
Nano Science and Technology Institute, University of Science and Technology of China, 166 Ren Ai Road, Suzhou 215123, China
*
Authors to whom correspondence should be addressed.
Received: 8 September 2017 / Revised: 10 October 2017 / Accepted: 16 October 2017 / Published: 24 October 2017
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Abstract

Marine organisms are prolific resources of guanidine-containing natural products with intriguing structures and promising biological activities. These molecules have therefore attracted the attention of chemists and biologists for their further studies towards potential drug leads. This review focused on the guanidine alkaloids derived from marine sources and discussed the recent progress on their isolation, synthesis and biological activities, covering the literature from the year 2010 to the present. View Full-Text
Keywords: marine guanidine alkaloids; sponge; mollusk; ascidian; total synthesis; biological activity marine guanidine alkaloids; sponge; mollusk; ascidian; total synthesis; biological activity
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Liu, J.; Li, X.-W.; Guo, Y.-W. Recent Advances in the Isolation, Synthesis and Biological Activity of Marine Guanidine Alkaloids. Mar. Drugs 2017, 15, 324.

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