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Mar. Drugs 2015, 13(9), 5993-6018; doi:10.3390/md13095993

Diatom-Specific Oligosaccharide and Polysaccharide Structures Help to Unravel Biosynthetic Capabilities in Diatoms

Laboratoire Glyco-MEV EA 4358, Université de Rouen, Normandie Université, Institut de Recherche et d’Innovation Biomédicale (IRIB), Végétale Agronomie Sol Innovation (VASI), Normandie Université, Faculté des Sciences et Techniques, 76821 Mont-Saint-Aignan, France
CNRS, Centre de Recherches sur les Macromolécules Végétales (CERMAV), Université Grenoble Alpes, CERMAV, F-38000 Grenoble, France
Institut Universitaire de France (IUF), 75005 Paris, France
Authors to whom correspondence should be addressed.
Academic Editor: Véronique Martin-Jézéquel
Received: 29 June 2015 / Revised: 10 September 2015 / Accepted: 11 September 2015 / Published: 18 September 2015
(This article belongs to the Special Issue Metabolites in Diatoms)
View Full-Text   |   Download PDF [684 KB, uploaded 21 September 2015]   |  


Diatoms are marine organisms that represent one of the most important sources of biomass in the ocean, accounting for about 40% of marine primary production, and in the biosphere, contributing up to 20% of global CO2 fixation. There has been a recent surge in developing the use of diatoms as a source of bioactive compounds in the food and cosmetic industries. In addition, the potential of diatoms such as Phaeodactylum tricornutum as cell factories for the production of biopharmaceuticals is currently under evaluation. These biotechnological applications require a comprehensive understanding of the sugar biosynthesis pathways that operate in diatoms. Here, we review diatom glycan and polysaccharide structures, thus revealing their sugar biosynthesis capabilities. View Full-Text
Keywords: microalgae; glycan; polysaccharide; diatom; exopolysaccharides; EPS; nucleotide sugars microalgae; glycan; polysaccharide; diatom; exopolysaccharides; EPS; nucleotide sugars

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Gügi, B.; Le Costaouec, T.; Burel, C.; Lerouge, P.; Helbert, W.; Bardor, M. Diatom-Specific Oligosaccharide and Polysaccharide Structures Help to Unravel Biosynthetic Capabilities in Diatoms. Mar. Drugs 2015, 13, 5993-6018.

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