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Mar. Drugs 2015, 13(3), 1519-1547; doi:10.3390/md13031519

Chitin and Chitosan as Direct Compression Excipients in Pharmaceutical Applications

Research and Innovation Center (RIC), The Jordanian Pharmaceutical Manufacturing Co., P.O. Box 94, Naor 11710, Jordan
Author to whom correspondence should be addressed.
Academic Editor: David Harding
Received: 18 December 2014 / Revised: 9 January 2015 / Accepted: 9 February 2015 / Published: 19 March 2015
(This article belongs to the Special Issue Advances in Marine Chitin and Chitosan)
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Despite the numerous uses of chitin and chitosan as new functional materials of high potential in various fields, they are still behind several directly compressible excipients already dominating pharmaceutical applications. There are, however, new attempts to exploit chitin and chitosan in co-processing techniques that provide a product with potential to act as a direct compression (DC) excipient. This review outlines the compression properties of chitin and chitosan in the context of DC pharmaceutical applications. View Full-Text
Keywords: chitin; chitosan; direct compression; co-processed excipients; solid formulation chitin; chitosan; direct compression; co-processed excipients; solid formulation

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Badwan, A.A.; Rashid, I.; Omari, M.M.A.; Darras, F.H. Chitin and Chitosan as Direct Compression Excipients in Pharmaceutical Applications. Mar. Drugs 2015, 13, 1519-1547.

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