New Briarane Diterpenoids from Taiwanese Soft Coral Briareum violacea
AbstractTen new briarane diterpenoids, briaviolides A–J (1–10), together with six known briaranes, solenolides A and D, excavatolide A, briaexcavatolide I, 4β-acetoxy-9-deacetystylatulide lactone and 9-deacetylstylatulide lactone, were isolated from the Taiwanese soft coral, Briareum violacea. Their structures were determined on the basis of spectroscopic data (1H- and 13C-NMR, 1H–1H COSY, HSQC, HMBC and NOESY), HR-MS and chemical methods. The absolute configuration of briaviolide A (1) was determined by X-ray crystallographic analysis. Compounds 5, 9 and derivative 11 showed moderate inhibitory activities on superoxide-anion generation and elastase release by human neutrophils in response to N-formyl-methionyl-leucyl-phenylalanine/ Cytochalasin B (fMLP/CB). View Full-Text
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Liaw, C.-C.; Cheng, Y.-B.; Lin, Y.-S.; Kuo, Y.-H.; Hwang, T.-L.; Shen, Y.-C. New Briarane Diterpenoids from Taiwanese Soft Coral Briareum violacea. Mar. Drugs 2014, 12, 4677-4692.
Liaw C-C, Cheng Y-B, Lin Y-S, Kuo Y-H, Hwang T-L, Shen Y-C. New Briarane Diterpenoids from Taiwanese Soft Coral Briareum violacea. Marine Drugs. 2014; 12(8):4677-4692.Chicago/Turabian Style
Liaw, Chia-Ching; Cheng, Yuan-Bin; Lin, Yun-Sheng; Kuo, Yao-Haur; Hwang, Tsong-Long; Shen, Ya-Ching. 2014. "New Briarane Diterpenoids from Taiwanese Soft Coral Briareum violacea." Mar. Drugs 12, no. 8: 4677-4692.