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Mar. Drugs 2013, 11(9), 3155-3167; doi:10.3390/md11093155
Review

Silaffins of Diatoms: From Applied Biotechnology to Biomedicine

1
 and
2,*
Received: 13 May 2013 / Revised: 29 July 2013 / Accepted: 12 August 2013 / Published: 26 August 2013
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Abstract

Silaffins are involved in the formation of the cell walls of diatoms. It is known that silaffins can precipitate silica in vitro, forming nano- and micro-particles in the shape of spheres and plates containing many pores. It is important to note that the deposition of silica and the particle morphology in the presence of silaffins affects chemical and physical agents (e.g., peptides, polyamines, phosphate, nitrogen, and the mechanical changes of the reaction mixture). It is believed that silaffins act as an organic matrix for silica-genesis and that silica pore size should reflect the pattern of a matrix. Here, biotechnology related to silaffins is discussed in the context of “a hypothesis of silaffin matrix” and “the LCPA-phosphate model”. We discuss the most promising area of silaffin biotechnology—the development of production methods for silicon structures with desired shapes and nanostructural properties that can be used to create biocompatible materials.
Keywords: silaffins; diatoms; silicon; nanomaterials; medicine silaffins; diatoms; silicon; nanomaterials; medicine
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Pamirsky, I.E.; Golokhvast, K.S. Silaffins of Diatoms: From Applied Biotechnology to Biomedicine. Mar. Drugs 2013, 11, 3155-3167.

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