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Mar. Drugs 2013, 11(7), 2501-2509; doi:10.3390/md11072501
Article

Parathyrsoidins A–D, Four New Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoides

1
,
1
,
2,3,* , 1,3
 and
1,3,*
1 Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan 2 Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan 3 Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan
* Authors to whom correspondence should be addressed.
Received: 22 April 2013 / Revised: 6 June 2013 / Accepted: 28 June 2013 / Published: 15 July 2013
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Abstract

Four new nardosinane-type sesquiterpenoids, parathyrsoidins A–D (14) were isolated from the soft coral Paralemnalia thyrsoides. The structures of parathyrsoidins A–D (14) were determined by extensive spectral analysis and their cytotoxicity against selected cancer cell lines as well as antiviral activity against human cytomegalovirus (HCMV) were evaluated in vitro.
Keywords: soft coral; Paralemnalia thyrsoides; parathyrsoidins A–D; cytotoxicity soft coral; Paralemnalia thyrsoides; parathyrsoidins A–D; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Tseng, Y.-J.; Lee, Y.-S.; Wang, S.-K.; Sheu, J.-H.; Duh, C.-Y. Parathyrsoidins A–D, Four New Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoides. Mar. Drugs 2013, 11, 2501-2509.

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