Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.

Abstract: A new C₄₇ polyoxygenated acetylenic acid, nepheliosyne B (2), along with the previously described nepheliosyne A (1), have been isolated from the New Caledonian marine sponge Niphates sp. Their structures have been elucidated on the basis of extensive spectroscopic analyses. These metabolites exhibited a moderate cytotoxicity against K562, U266, SKM1, and Kasumi cancer cell lines.

Keywords: marine natural products; highly oxygenated polyacetylenes; marine sponges; Porifera; Haplosclerida

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MDPI and ACS Style

Legrave, N.; Hamrouni-Buonomo, S.; Dufies, M.; Guérineau, V.; Vacelet, J.; Auberger, P.; Amade, P.; Mehiri, M. Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.. Mar. Drugs 2013, 11, 2282-2292.

AMA Style

Legrave N, Hamrouni-Buonomo S, Dufies M, Guérineau V, Vacelet J, Auberger P, Amade P, Mehiri M. Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.. Marine Drugs. 2013; 11(7):2282-2292.

Chicago/Turabian Style

Legrave, Nathalie; Hamrouni-Buonomo, Souhir; Dufies, Maeva; Guérineau, Vincent; Vacelet, Jean; Auberger, Patrick; Amade, Philippe; Mehiri, Mohamed. 2013. "Nepheliosyne B, a New Polyacetylenic Acid from the New Caledonian Marine Sponge Niphates sp.." Mar. Drugs 11, no. 7: 2282-2292.

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