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Mar. Drugs 2013, 11(5), 1602-1643; doi:10.3390/md11051602
Review

Meroterpenes from Marine Invertebrates: Structures, Occurrence, and Ecological Implications

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Received: 19 March 2013 / Revised: 7 April 2013 / Accepted: 7 May 2013 / Published: 17 May 2013
(This article belongs to the Special Issue Marine Secondary Metabolites)

Abstract

Meroterpenes are widely distributed among marine organisms; they are particularly abundant within brown algae, but other important sources include microorganisms and invertebrates. In the present review the structures and bioactivities of meroterpenes from marine invertebrates, mainly sponges and tunicates, are summarized. More than 300 molecules, often complex and with unique skeletons originating from intra- and inter-molecular cyclizations, and/or rearrangements, are illustrated. The reported syntheses are mentioned. The issue of a potential microbial link to their biosynthesis is also shortly outlined.
Keywords: meroterpenes; terpene quinone; terpene hydroquinone; sponges; ascidians; soft corals meroterpenes; terpene quinone; terpene hydroquinone; sponges; ascidians; soft corals
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Menna, M.; Imperatore, C.; D'Aniello, F.; Aiello, A. Meroterpenes from Marine Invertebrates: Structures, Occurrence, and Ecological Implications. Mar. Drugs 2013, 11, 1602-1643.

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