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Meroterpenes from Marine Invertebrates: Structures, Occurrence, and Ecological Implications
The NeaNat Group, Dipartimento di Farmacia, Università degli Studi di Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy
* Author to whom correspondence should be addressed.
Received: 19 March 2013; in revised form: 7 April 2013 / Accepted: 7 May 2013 / Published: 17 May 2013
Abstract: Meroterpenes are widely distributed among marine organisms; they are particularly abundant within brown algae, but other important sources include microorganisms and invertebrates. In the present review the structures and bioactivities of meroterpenes from marine invertebrates, mainly sponges and tunicates, are summarized. More than 300 molecules, often complex and with unique skeletons originating from intra- and inter-molecular cyclizations, and/or rearrangements, are illustrated. The reported syntheses are mentioned. The issue of a potential microbial link to their biosynthesis is also shortly outlined.
Keywords: meroterpenes; terpene quinone; terpene hydroquinone; sponges; ascidians; soft corals
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Menna, M.; Imperatore, C.; D'Aniello, F.; Aiello, A. Meroterpenes from Marine Invertebrates: Structures, Occurrence, and Ecological Implications. Mar. Drugs 2013, 11, 1602-1643.
Menna M, Imperatore C, D'Aniello F, Aiello A. Meroterpenes from Marine Invertebrates: Structures, Occurrence, and Ecological Implications. Marine Drugs. 2013; 11(5):1602-1643.
Menna, Marialuisa; Imperatore, Concetta; D'Aniello, Filomena; Aiello, Anna. 2013. "Meroterpenes from Marine Invertebrates: Structures, Occurrence, and Ecological Implications." Mar. Drugs 11, no. 5: 1602-1643.