Mar. Drugs 2013, 11(5), 1602-1643; doi:10.3390/md11051602
Review

Meroterpenes from Marine Invertebrates: Structures, Occurrence, and Ecological Implications

The NeaNat Group, Dipartimento di Farmacia, Università degli Studi di Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy
* Author to whom correspondence should be addressed.
Received: 19 March 2013; in revised form: 7 April 2013 / Accepted: 7 May 2013 / Published: 17 May 2013
(This article belongs to the Special Issue Marine Secondary Metabolites)
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Abstract: Meroterpenes are widely distributed among marine organisms; they are particularly abundant within brown algae, but other important sources include microorganisms and invertebrates. In the present review the structures and bioactivities of meroterpenes from marine invertebrates, mainly sponges and tunicates, are summarized. More than 300 molecules, often complex and with unique skeletons originating from intra- and inter-molecular cyclizations, and/or rearrangements, are illustrated. The reported syntheses are mentioned. The issue of a potential microbial link to their biosynthesis is also shortly outlined.
Keywords: meroterpenes; terpene quinone; terpene hydroquinone; sponges; ascidians; soft corals

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MDPI and ACS Style

Menna, M.; Imperatore, C.; D'Aniello, F.; Aiello, A. Meroterpenes from Marine Invertebrates: Structures, Occurrence, and Ecological Implications. Mar. Drugs 2013, 11, 1602-1643.

AMA Style

Menna M, Imperatore C, D'Aniello F, Aiello A. Meroterpenes from Marine Invertebrates: Structures, Occurrence, and Ecological Implications. Marine Drugs. 2013; 11(5):1602-1643.

Chicago/Turabian Style

Menna, Marialuisa; Imperatore, Concetta; D'Aniello, Filomena; Aiello, Anna. 2013. "Meroterpenes from Marine Invertebrates: Structures, Occurrence, and Ecological Implications." Mar. Drugs 11, no. 5: 1602-1643.

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