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Marine Drugs Best Paper Award 2013
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Probing a Coral Genome for Components of the Photoprotective Scytonemin Biosynthetic Pathway and the 2-Aminoethylphosphonate Pathway
Mar. Drugs 2013, 11(2), 571-580; doi:10.3390/md11020571

New Steroids from the Soft Coral Nephthea chabrolii

Received: 9 January 2013 / Revised: 18 February 2013 / Accepted: 18 February 2013 / Published: 22 February 2013
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A new cytotoxic 19-oxygenated steroid, nebrosteroid Q (1) and two new cytotoxic 19-norergosterols, nebrosteroids R and S (2 and 3) were isolated from the soft coral Nephthea chabrolii collected at San-Hsian-Tai. The structures of nebrosteroids Q–S (13) were elucidated by spectral analysis, and their cytotoxicity against selected cancer cells as well as antiviral activity against human cytomegalovirus (HCMV) were measured in vitro.
Keywords: Nephthea chabrolii; 19-oxygenated steroid; norergosterol; cytotoxicity Nephthea chabrolii; 19-oxygenated steroid; norergosterol; cytotoxicity
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Wang, S.-K.; Puu, S.-Y.; Duh, C.-Y. New Steroids from the Soft Coral Nephthea chabrolii. Mar. Drugs 2013, 11, 571-580.

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