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Mar. Drugs 2013, 11(11), 4585-4593; doi:10.3390/md11114585
Article

Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.

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Received: 26 August 2013 / Revised: 17 October 2013 / Accepted: 31 October 2013 / Published: 14 November 2013
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Abstract

A new eunicellin diterpenoid, cladieunicellin I (1), and a new natural eunicellin, litophynin I diacetate (2), were isolated from a Formosan soft coral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods and by comparison of the spectral data with those of related analogues. Eunicellin 1 exhibited significant cytotoxicity toward the DLD-1 human colorectal adenocarcinoma cells.
Keywords: eunicellin; Cladiella; cladieunicellin; litophynin; cytotoxicity eunicellin; Cladiella; cladieunicellin; litophynin; cytotoxicity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Chen, T.-H.; Lu, M.-C.; Chang, Y.-C.; Su, Y.-D.; Chen, Y.-H.; Lin, N.-C.; Fang, L.-S.; Wu, Y.-C.; Sung, P.-J. Discovery of New Eunicellin-Based Diterpenoids from a Formosan Soft Coral Cladiella sp.. Mar. Drugs 2013, 11, 4585-4593.

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