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Mar. Drugs 2013, 11(11), 4318-4327; doi:10.3390/md11114318

New Diterpenoids from Soft Coral Sarcophyton ehrenbergi

3 and 1,3,*
1 Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan 2 Department of Microbiology, Kaohsiung Medical University, Kaohsiung 807, Taiwan 3 Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan
* Author to whom correspondence should be addressed.
Received: 23 September 2013 / Revised: 18 October 2013 / Accepted: 22 October 2013 / Published: 30 October 2013
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Continuing chemical investigation on the acetone extracts of the soft coral Sarcophyton ehrenbergi collected off the coast of San-hsian-tai, Taitong County, Taiwan led to the isolation of two new diterpenoids, ehrenbergol C and acetyl ehrenberoxide B (1 and 2). The structures of these isolated metabolites were elucidated through extensive spectroscopic analyses. Moreover, in vitro tests show that compounds 1 and 2 displayed antiviral activity towards human cytomegalovirus, with EC50 of 20 and 8.0 µg/mL, respectively.
Keywords: Sarcophyton ehrenbergi; diterpenoids; cytotoxicity; anti-HCMV Sarcophyton ehrenbergi; diterpenoids; cytotoxicity; anti-HCMV
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Wang, S.-K.; Hsieh, M.-K.; Duh, C.-Y. New Diterpenoids from Soft Coral Sarcophyton ehrenbergi. Mar. Drugs 2013, 11, 4318-4327.

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