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Mar. Drugs 2013, 11(10), 4050-4057; doi:10.3390/md11104050
Communication

Red Algal Bromophenols as Glucose 6-Phosphate Dehydrogenase Inhibitors

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Received: 8 August 2013 / Revised: 31 August 2013 / Accepted: 2 September 2013 / Published: 22 October 2013
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Abstract

Five bromophenols isolated from three Rhodomelaceae algae (Laurencia nipponica, Polysiphonia morrowii, Odonthalia corymbifera) showed inhibitory effects against glucose 6-phosphate dehydrogenase (G6PD). Among them, the symmetric bromophenol dimer (5) showed the highest inhibitory activity against G6PD.
Keywords: bromophenol; Rhodomelaceae; pentose phosphate pathway (PPP); glucose 6-phosphate dehydrogenase; inhibition bromophenol; Rhodomelaceae; pentose phosphate pathway (PPP); glucose 6-phosphate dehydrogenase; inhibition
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Mikami, D.; Kurihara, H.; Kim, S.M.; Takahashi, K. Red Algal Bromophenols as Glucose 6-Phosphate Dehydrogenase Inhibitors. Mar. Drugs 2013, 11, 4050-4057.

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