Next Article in Journal
Sinularones A–I, New Cyclopentenone and Butenolide Derivatives from a Marine Soft Coral Sinularia sp. and Their Antifouling Activity
Previous Article in Journal
Marine Cyclotripeptide X-13 Promotes Angiogenesis in Zebrafish and Human Endothelial Cells via PI3K/Akt/eNOS Signaling Pathways
Mar. Drugs 2012, 10(6), 1321-1330; doi:10.3390/md10061321

New Briarane Diterpenoids from the Gorgonian Coral Junceella juncea

1 School of Pharmacy, College of Medicine, National Taiwan University, Jen-Ai Rd. Sec. 1, Taipei 101-200, Taiwan 2 Institute of Marine Biotechnology and Resources, National Sun Yat-sen University, 70 Lien-Hai Road, Kaohsiung 80424, Taiwan 3 Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan
* Author to whom correspondence should be addressed.
Received: 29 March 2012 / Revised: 18 May 2012 / Accepted: 29 May 2012 / Published: 7 June 2012
View Full-Text   |   Download PDF [688 KB, uploaded 24 February 2015]   |   Browse Figures


Chemical investigation of Junceella juncea has resulted in the isolation of three new briaranes designated juncenolides M–O (13). The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY) and HRMS. Compound 1 is a new chlorinated briarane while compound 3 contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated.
Keywords: Junceella juncea; briaranes; anti-inflammatory activity Junceella juncea; briaranes; anti-inflammatory activity
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
MDPI and ACS Style

Chang, J.-Y.; Liaw, C.-C.; Fazary, A.E.; Hwang, T.-L.; Shen, Y.-C. New Briarane Diterpenoids from the Gorgonian Coral Junceella juncea. Mar. Drugs 2012, 10, 1321-1330.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here


Cited By

[Return to top]
Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert