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Mar. Drugs 2012, 10(6), 1321-1330; doi:10.3390/md10061321
Article

New Briarane Diterpenoids from the Gorgonian Coral Junceella juncea

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Received: 29 March 2012 / Revised: 18 May 2012 / Accepted: 29 May 2012 / Published: 7 June 2012
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Abstract

Chemical investigation of Junceella juncea has resulted in the isolation of three new briaranes designated juncenolides M–O (13). The structures of these compounds were determined by spectroscopic analysis including 2D-NMR (COSY, HMBC and NOESY) and HRMS. Compound 1 is a new chlorinated briarane while compound 3 contains a rare methyl ester at C-16. The anti-inflammatory activities tested on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB were evaluated.
Keywords: Junceella juncea; briaranes; anti-inflammatory activity Junceella juncea; briaranes; anti-inflammatory activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Chang, J.-Y.; Liaw, C.-C.; Fazary, A.E.; Hwang, T.-L.; Shen, Y.-C. New Briarane Diterpenoids from the Gorgonian Coral Junceella juncea. Mar. Drugs 2012, 10, 1321-1330.

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