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Mar. Drugs 2012, 10(12), 2741-2748; doi:10.3390/md10122741
Article

Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.

1
, 1
, 2
, 3
 and 1,*
Received: 24 October 2012; in revised form: 23 November 2012 / Accepted: 26 November 2012 / Published: 30 November 2012
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Abstract: Five new diterpenoids 15 were isolated from an Okinawan soft coral, Cespitularia sp., together with the known diterpenoid, alcyonolide (6). New diterpenoid structures were elucidated by spectroscopic methods and by comparison of their NMR data with those of related compounds. Alcyonolide (6) was cytotoxic against HCT 116 cells (IC50 5.85 μM), while these new diterpenoids 15 were much less active (IC50 28.2–91.4 μM).
Keywords: Cespitularia; cytotoxicity; diterpenoid; HCT 116 cells; alcyonolide Cespitularia; cytotoxicity; diterpenoid; HCT 116 cells; alcyonolide
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Roy, P.K.; Maarisit, W.; Roy, M.C.; Taira, J.; Ueda, K. Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.. Mar. Drugs 2012, 10, 2741-2748.

AMA Style

Roy PK, Maarisit W, Roy MC, Taira J, Ueda K. Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.. Marine Drugs. 2012; 10(12):2741-2748.

Chicago/Turabian Style

Roy, Prodip K.; Maarisit, Wilmar; Roy, Michael C.; Taira, Junsei; Ueda, Katsuhiro. 2012. "Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.." Mar. Drugs 10, no. 12: 2741-2748.



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