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Pharmaceuticals 2010, 3(5), 1304-1310; doi:10.3390/ph3051304
Review

The Role of Non-Steroidal Anti-Inflammatory Drugs in Renal Colic

*  and
Bristol Urological Institute, Southmead Hospital, Westbury-on-Trym, Bristol, BS10 5NB, UK
* Author to whom correspondence should be addressed.
Received: 4 March 2010 / Revised: 17 April 2010 / Accepted: 21 April 2010 / Published: 28 April 2010
(This article belongs to the collection Non-Steroidal Anti-Inflammatory Drugs)
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Abstract

NSAIDs provide optimal analgesia in renal colic due to the reduction in glomerular filtration and renal pelvic pressure, ureteric peristalsis and ureteric oedema. Prevention of glomerular afferent arteriolar vasodilatation renders these patients at risk of renal impairment. NSAIDs have the additional benefit of reducing the number of new colic episodes and preventing subsequent readmission to hospital. Despite recent work promoting the use of pharmacological agents to improve stone passage rates, NSAIDs do not appear to reduce the time to stone passage or increase the likelihood of stone passage in renal colic.
Keywords: renal colic; ureteric stone; Non-steroidal anti-inflammatory drugs renal colic; ureteric stone; Non-steroidal anti-inflammatory drugs
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Davenport, K.; Waine, E. The Role of Non-Steroidal Anti-Inflammatory Drugs in Renal Colic. Pharmaceuticals 2010, 3, 1304-1310.

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