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The Role of Non-Steroidal Anti-Inflammatory Drugs in Renal Colic
Bristol Urological Institute, Southmead Hospital, Westbury-on-Trym, Bristol, BS10 5NB, UK
* Author to whom correspondence should be addressed.
Received: 4 March 2010; in revised form: 17 April 2010 / Accepted: 21 April 2010 / Published: 28 April 2010
Abstract: NSAIDs provide optimal analgesia in renal colic due to the reduction in glomerular filtration and renal pelvic pressure, ureteric peristalsis and ureteric oedema. Prevention of glomerular afferent arteriolar vasodilatation renders these patients at risk of renal impairment. NSAIDs have the additional benefit of reducing the number of new colic episodes and preventing subsequent readmission to hospital. Despite recent work promoting the use of pharmacological agents to improve stone passage rates, NSAIDs do not appear to reduce the time to stone passage or increase the likelihood of stone passage in renal colic.
Keywords: renal colic; ureteric stone; Non-steroidal anti-inflammatory drugs
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Cite This Article
MDPI and ACS Style
Davenport, K.; Waine, E. The Role of Non-Steroidal Anti-Inflammatory Drugs in Renal Colic. Pharmaceuticals 2010, 3, 1304-1310.
Davenport K, Waine E. The Role of Non-Steroidal Anti-Inflammatory Drugs in Renal Colic. Pharmaceuticals. 2010; 3(5):1304-1310.
Davenport, Kim; Waine, Elizabeth. 2010. "The Role of Non-Steroidal Anti-Inflammatory Drugs in Renal Colic." Pharmaceuticals 3, no. 5: 1304-1310.