Next Article in Journal
Systematic Analysis of Pharmaceutical Preparations of Chondroitin Sulfate Combined with Glucosamine
Next Article in Special Issue
Role of TRPM7 in Cancer: Potential as Molecular Biomarker and Therapeutic Target
Previous Article in Journal
Development of a Glycosaminoglycan Derived, Selectin Targeting Anti-Adhesive Coating to Treat Endothelial Cell Dysfunction
Previous Article in Special Issue
Modulation of TRP Channel Activity by Hydroxylation and Its Therapeutic Potential
Article Menu
Issue 2 (June) cover image

Export Article

Open AccessReview
Pharmaceuticals 2017, 10(2), 37; doi:10.3390/ph10020037

Development of TRPM8 Antagonists to Treat Chronic Pain and Migraine

1
Pacific University School of Physical Therapy, Hillsboro, OR 97123, USA
2
One Amgen Center Dr, Thousand Oaks, CA 91320, USA
*
Author to whom correspondence should be addressed.
Academic Editors: Susan M. Huang, Arpad Szallasi and Jean Jacques Vanden Eynde
Received: 16 February 2017 / Revised: 16 March 2017 / Accepted: 23 March 2017 / Published: 30 March 2017
View Full-Text   |   Download PDF [212 KB, uploaded 30 March 2017]

Abstract

A review. Development of pharmaceutical antagonists of transient receptor potential melastatin 8 (TRPM8) have been pursued for the treatment of chronic pain and migraine. This review focuses on the current state of this progress. View Full-Text
Keywords: transient receptor potential melastatin 8 (TRPM*); pain; menthol; cold hyperalgesia; cold analgesia; mechanical hyperalgesia; migraine transient receptor potential melastatin 8 (TRPM*); pain; menthol; cold hyperalgesia; cold analgesia; mechanical hyperalgesia; migraine
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Weyer, A.D.; Lehto, S.G. Development of TRPM8 Antagonists to Treat Chronic Pain and Migraine. Pharmaceuticals 2017, 10, 37.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Pharmaceuticals EISSN 1424-8247 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top