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Pharmaceuticals 2017, 10(1), 29; doi:10.3390/ph10010029

Theranostic Value of Multimers: Lessons Learned from Trimerization of Neurotensin Receptor Ligands and Other Targeting Vectors

1
Department of Nuclear Medicine, Molecular Imaging and Radiochemistry, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054 Erlangen, Germany
2
Department of Chemistry and Pharmacy, Medicinal Chemistry, Emil Fischer Center, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schuhstraße 19, 91052 Erlangen, Germany
3
Lehrstuhl für Pharmazeutische Radiochemie, Technische Universität München, Walther-Meißner-Strasse 3, 85748 Garching, Germany
*
Author to whom correspondence should be addressed.
Academic Editors: Klaus Kopka and Elisabeth Eppard
Received: 31 January 2017 / Accepted: 8 March 2017 / Published: 10 March 2017
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Note: In lieu of an abstract, this is an excerpt from the first page.

Excerpt

Neurotensin receptor 1 (NTS1) is overexpressed on a variety of cancer entities; for example, prostate cancer, ductal pancreatic adenocarcinoma, and breast cancer. Therefore, it represents an interesting target for the diagnosis of these cancers types by positron emission tomography (PET) [...] View Full-Text
Keywords: neurotensin; neurotensin receptor; NTS1; positron emission tomography; PET; gallium68; TRAP; multimerization neurotensin; neurotensin receptor; NTS1; positron emission tomography; PET; gallium68; TRAP; multimerization
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Maschauer, S.; Einsiedel, J.; Reich, D.; Hübner, H.; Gmeiner, P.; Wester, H.-J.; Prante, O.; Notni, J. Theranostic Value of Multimers: Lessons Learned from Trimerization of Neurotensin Receptor Ligands and Other Targeting Vectors. Pharmaceuticals 2017, 10, 29.

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