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Sensors 2009, 9(7), 5600-5636; doi:10.3390/s90705600

DNA Sensors with Diamond as a Promising Alternative Transducer Material

1
Biomedical Research Institute, School for Life Sciences, Hasselt University and Transnationale Universiteit Limburg, Agoralaan, Bldg. C, B-3590 Diepenbeek, Belgium
2
Institute for Materials Research, School for Life Sciences, Hasselt University and Transnationale Universiteit Limburg, Wetenschapspark 1, B-3590 Diepenbeek, Belgium
*
Author to whom correspondence should be addressed.
Received: 5 June 2009 / Revised: 2 July 2009 / Accepted: 3 July 2009 / Published: 14 July 2009
(This article belongs to the Special Issue DNA Sensors and Biosensors)
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Abstract

Bio-electronics is a scientific field coupling the achievements in biology with electronics to obtain higher sensitivity, specificity and speed. Biosensors have played a pivotal role, and many have become established in the clinical and scientific world. They need to be sensitive, specific, fast and cheap. Electrochemical biosensors are most frequently cited in literature, often in the context of DNA sensing and mutation analysis. However, many popular electrochemical transduction materials, such as silicon, are susceptible to hydrolysis, leading to loss of bioreceptor molecules from the surface. Hence, increased attention has been shifted towards diamond, which surpasses silicon on many levels. View Full-Text
Keywords: DNA; single nucleotide mismatch; aptamers; bioconjugates; biosensors; impedance sensors; SPR; fluorescence sensors DNA; single nucleotide mismatch; aptamers; bioconjugates; biosensors; impedance sensors; SPR; fluorescence sensors
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Vermeeren, V.; Wenmackers, S.; Wagner, P.; Michiels, L. DNA Sensors with Diamond as a Promising Alternative Transducer Material. Sensors 2009, 9, 5600-5636.

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