A Miniature Probe for Ultrasonic Penetration of a Single Cell
AbstractAlthough ultrasound cavitation must be avoided for safe diagnostic applications, the ability of ultrasound to disrupt cell membranes has taken on increasing significance as a method to facilitate drug and gene delivery. A new ultrasonic resonance driving method is introduced to penetrate rigid wall plant cells or oocytes with springy cell membranes. When a reasonable design is created, ultrasound can gather energy and increase the amplitude factor. Ultrasonic penetration enables exogenous materials to enter cells without damaging them by utilizing instant acceleration. This paper seeks to develop a miniature ultrasonic probe experiment system for cell penetration. A miniature ultrasonic probe is designed and optimized using the Precise Four Terminal Network Method and Finite Element Method (FEM) and an ultrasonic generator to drive the probe is designed. The system was able to successfully puncture a single fish cell. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Wu, T.; Zhou, Z.; Wang, Q.; Yang, X.; Xiao, M. A Miniature Probe for Ultrasonic Penetration of a Single Cell. Sensors 2009, 9, 3325-3336.
Wu T, Zhou Z, Wang Q, Yang X, Xiao M. A Miniature Probe for Ultrasonic Penetration of a Single Cell. Sensors. 2009; 9(5):3325-3336.Chicago/Turabian Style
Wu, Ting; Zhou, Zhaoying; Wang, Qun; Yang, Xing; Xiao, Mingfei. 2009. "A Miniature Probe for Ultrasonic Penetration of a Single Cell." Sensors 9, no. 5: 3325-3336.